| IED ID | IndEnz0002007813 |
| Enzyme Type ID | protease007813 |
| Protein Name |
Mitochondrial-processing peptidase subunit alpha Alpha-MPP Inactive zinc metalloprotease alpha Ubiquinol-cytochrome-c reductase subunit II EC 7.1.1.8 |
| Gene Name | MPP |
| Organism | Solanum tuberosum (Potato) |
| Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae asterids lamiids Solanales Solanaceae Solanoideae Solaneae Solanum Solanum tuberosum (Potato) |
| Enzyme Sequence | MYRCASSRLSSLKARQGNRVLTRFSSSAAVATKPSGGLFSWITGDTSSSVTPLDFPLNDVKLSPPLPDYVEPAKTQITTLANGLKVASEASVNPAASIGLYVDCGSIYETPASYGATHLLERMAFKSTLNRSHLRIVREIEAIGGNVTASASREHMIYTYDALKTYVPQMVEMLADCVRNPAFLDWEVKEQLEKVKAEISEYSKNPQHLLLEAVHSAGYAGPYGNSLMATEATINRLNSTVLEEFVAENYTAPRMVLAASGVEHEEFLKVAEPLLSDLPKVATIEEPKPVYVGGDYRCQADAEMTHFALAFEVPGGWMSEKESMTLTVLQMLMGGGGSFSAGGPGKGMYSRLYLRVLNQYPQIHAFSAFSSIYNNTGLFGIQGTTSSDFGPQAVDVAVKELIAVANPSEVDQVQLNRAKQATKSAILMNLESRMVASEDIGRQLLTYGERNPVEHFLKAIDAVSAKDIASVVQKLISSPLTMASYGDVLSLPSYDAVSSRFRSK |
| Enzyme Length | 504 |
| Uniprot Accession Number | P29677 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=a quinol + 2 Fe(III)-[cytochrome c](out) = a quinone + 2 Fe(II)-[cytochrome c](out) + 2 H(+)(out); Xref=Rhea:RHEA:11484, Rhea:RHEA-COMP:10350, Rhea:RHEA-COMP:14399, ChEBI:CHEBI:15378, ChEBI:CHEBI:24646, ChEBI:CHEBI:29033, ChEBI:CHEBI:29034, ChEBI:CHEBI:132124; EC=7.1.1.8; |
| DNA Binding | |
| EC Number | 7.1.1.8 |
| Enzyme Function | FUNCTION: Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins. {ECO:0000250|UniProtKB:P11914}.; FUNCTION: This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. Mediates formation of the complex between cytochromes c and c1. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Transit peptide (1) |
| Keywords | Direct protein sequencing;Electron transport;Membrane;Mitochondrion;Mitochondrion inner membrane;Reference proteome;Respiratory chain;Transit peptide;Translocase;Transport |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Mitochondrion inner membrane. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 14983062; |
| Motif | |
| Gene Encoded By | |
| Mass | 54,677 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | RHEA:11484 |
| Cross Reference Brenda |