| IED ID |
IndEnz0002007847 |
| Enzyme Type ID |
protease007847 |
| Protein Name |
pH-response transcription factor pacC/RIM101
|
| Gene Name |
pacC |
| Organism |
Gibberella fujikuroi (Bakanae and foot rot disease fungus) (Fusarium fujikuroi) |
| Taxonomic Lineage |
cellular organisms
Eukaryota
Opisthokonta
Fungi
Dikarya
Ascomycota
saccharomyceta
Pezizomycotina
leotiomyceta
sordariomyceta
Sordariomycetes
Hypocreomycetidae
Hypocreales
Nectriaceae
Fusarium
Fusarium fujikuroi species complex
Gibberella fujikuroi (Bakanae and foot rot disease fungus) (Fusarium fujikuroi)
|
| Enzyme Sequence |
MSPPAPEQKPQLQQQQQQQGSSSGDSSSGSANDSKSVTPAPSATSNTSQSSTAPSTSSDDNLICRWNACNQKFPAPEALYEHICERHVGRKSTNNLNLTCQWNSCRTTTVKRDHITSHIRVHVPLKPHKCDFCGKSFKRPQDLKKHVKTHADDSVLVRPSQDPQGGLNYRPQPPKGMSHLDSSPRLYYDHTGQMRTNAAAFAHQAGHPSGGYYAPQPSTNYGLYFNQPPINNARTEHLGYSAAAGGYDRKRTYDMVDDFFGSAKRRQIDPSSYAQIGRSLMPLHGNLSVPNGPMTATEQYMPQPAPAPVHAGPTPSQNPLAQQYYLPMPSARTQKDLIHIDTILGQMQDTIYENANHATAGVHIHHAENGFNGYRNTPSPPTSHRSPTGMHVGADGYQPVSAASMASPLTAISSTGTPAVTPPSSSMSYTSGHSPSPSSSAMSPQSRHGSTASVMYPTLPTSLPAVSQGFGHSATTTLGPSFDGSERRRYSGGMLQRARAGPLPLPREDTSGASTPKASESALSVGSPSSESDVSDATREREEQYDRWLENMRVIETLREYVRGRLERKEFVEDNESPRSSHSDAMDVDPKSPQAPPRELGTPREGSSLYPILRMPGA |
| Enzyme Length |
618 |
| Uniprot Accession Number |
Q8J1U9 |
| Absorption |
|
| Active Site |
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| Activity Regulation |
|
| Binding Site |
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| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
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| Enzyme Function |
FUNCTION: Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH. At alkaline ambient pH, activates transcription of alkaline-expressed genes (including pacC itself) and represses transcription of acid-expressed genes (By similarity). {ECO:0000250}. |
| Temperature Dependency |
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| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
|
| Features |
Chain (1); Compositional bias (4); Motif (2); Region (5); Zinc finger (3) |
| Keywords |
Activator;Cytoplasm;DNA-binding;Metal-binding;Nucleus;Repeat;Repressor;Transcription;Transcription regulation;Zinc;Zinc-finger |
| Interact With |
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| Induction |
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| Subcellular Location |
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
| Modified Residue |
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| Post Translational Modification |
PTM: Activated by C-terminal proteolytic cleavage by signaling protease (probably palB/RIM13) at neutral to alkaline ambient pH. {ECO:0000250}. |
| Signal Peptide |
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| Structure 3D |
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| Cross Reference PDB |
- |
| Mapped Pubmed ID |
- |
| Motif |
MOTIF 456..459; /note=YPX[LI] motif 1; MOTIF 610..613; /note=YPX[LI] motif 2 |
| Gene Encoded By |
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| Mass |
66,994 |
| Kinetics |
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| Metal Binding |
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| Rhea ID |
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| Cross Reference Brenda |
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