| IED ID | IndEnz0002007962 |
| Enzyme Type ID | protease007962 |
| Protein Name |
Portal protein Cleaved into: Protein B* |
| Gene Name | gene 4 |
| Organism | Escherichia phage N15 (Bacteriophage N15) |
| Taxonomic Lineage | Viruses Duplodnaviria Heunggongvirae Uroviricota Caudoviricetes Caudovirales Siphoviridae (phages with long non-contractile tails) Ravinvirus Escherichia phage N15 (Bacteriophage N15) |
| Enzyme Sequence | MKIPSLVGPDGKTSLREYAGYHGGGGGFGGQLRGWNPPSESADAALLPNYSRGNARADDLVRNNGYAANAVQLHQDHIVGSFFRLSYRPSWRYLGINEEDSRAFSRDVEAAWNEYAEDDFCGIDAERKRTFTMMIREGVAMHAFNGELCVQATWDSDSTRLFRTQFKMVSPKRVSNPNNIGDTRNCRAGVKINDSGAALGYYVSDDGYPGWMAQNWTYIPRELPGGRPSFIHVFEPMEDGQTRGANAFYSVMEQMKMLDTLQNTQLQSAIVKAMYAATIESELDTQSAMDFILGADNKEQQSKLTGWLGEMAAYYSAAPVRLGGARVPHLLPGDSLNLQSAQDTDNGYSTFEQSLLRYIAAGLGVSYEQLSRNYSQMSYSTARASANESWAYFMGRRKFVASRQACQMFLCWLEEAIVRRVVTLPSKARFSFQEARTAWGNANWIGSGRMAIDGLKEVQEAVMLIEAGLSTYEKECAKRGDDYQEIFAQQVRESMERRAAGLNPPAWAAAAFEAGVKKSNEEEQDGARAA |
| Enzyme Length | 530 |
| Uniprot Accession Number | O64319 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: Forms the portal vertex of the capsid. This portal plays critical roles in head assembly, genome packaging, neck/tail attachment, and genome ejection. The portal protein multimerizes as a single ring-shaped homododecamer arranged around a central channel. Binds to the terminase subunits to form the packaging machine. {ECO:0000255|HAMAP-Rule:MF_04135}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (2); Site (1) |
| Keywords | Capsid protein;DNA-binding;Reference proteome;Viral capsid assembly;Viral genome ejection through host cell envelope;Viral genome packaging;Viral long flexible tail ejection system;Viral penetration into host cytoplasm;Viral release from host cell;Virion;Virus entry into host cell |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Virion {ECO:0000255|HAMAP-Rule:MF_04135}. |
| Modified Residue | |
| Post Translational Modification | PTM: Proteolytically cleaved by the viral protease during capsid maturation. {ECO:0000255|HAMAP-Rule:MF_04135}. |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 58,855 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |