| IED ID | IndEnz0002007974 |
| Enzyme Type ID | protease007974 |
| Protein Name |
Portal protein Capsid protein pb7 |
| Gene Name | ORF141 T5.152 T5p148 |
| Organism | Escherichia phage T5 (Enterobacteria phage T5) |
| Taxonomic Lineage | Viruses Duplodnaviria Heunggongvirae Uroviricota Caudoviricetes Caudovirales Demerecviridae Markadamsvirinae Tequintavirus Escherichia phage T5 (Enterobacteria phage T5) |
| Enzyme Sequence | MGFKSWITEKLNPGQRIIRDMEPVSHRTNRKPFTTGQAYSKIEILNRTANMVIDSAAECSYTVGDKYNIVTYANGVKTKTLDTLLNVRPNPFMDISTFRRLVVTDLLFEGCAYIYWDGTSLYHVPAALMQVEADANKFIKKFIFNNQINYRVDEIIFIKDNSYVCGTNSQISGQSRVATVIDSLEKRSKMLNFKEKFLDNGTVIGLILETDEILNKKLRERKQEELQLDYNPSTGQSSVLILDGGMKAKPYSQISSFKDLDFKEDIEGFNKSICLAFGVPQVLLDGGNNANIRPNIELFYYMTIIPMLNKLTSSLTFFFGYKITPNTKEVAALTPDKEAEAKHLTSLVNNGIITGNEARSELNLEPLDDEQMNKIRIPANVAGSATGVSGQEGGRPKGSTEGD |
| Enzyme Length | 403 |
| Uniprot Accession Number | Q6QGD5 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: Forms the portal vertex of the capsid and plays a role in governing correct capsid geometry (PubMed:26616586). This portal plays critical roles in capsid assembly, genome packaging, head completion protein attachment, and genome ejection (By similarity). The portal protein multimerizes as a single ring-shaped homododecamer arranged around a central channel (By similarity). Binds to the terminase subunits to form the packaging machine (By similarity). {ECO:0000250|UniProtKB:P25480, ECO:0000269|PubMed:26616586}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Propeptide (1); Region (1); Site (1) |
| Keywords | Capsid protein;Direct protein sequencing;Late protein;Reference proteome;Viral capsid assembly;Viral genome ejection through host cell envelope;Viral genome packaging;Viral long flexible tail ejection system;Viral penetration into host cytoplasm;Viral release from host cell;Virion;Virus entry into host cell |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Virion {ECO:0000269|PubMed:24198424}. Note=Forms the portal complex located at one vertex of the capsid. {ECO:0000269|PubMed:24198424}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 45,087 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |