| IED ID | IndEnz0002007981 |
| Enzyme Type ID | protease007981 |
| Protein Name |
Portal protein B GpB Minor capsid protein B Cleaved into: Protein B* |
| Gene Name | B lambdap04 |
| Organism | Escherichia phage lambda (Bacteriophage lambda) |
| Taxonomic Lineage | Viruses Duplodnaviria Heunggongvirae Uroviricota Caudoviricetes Caudovirales Siphoviridae (phages with long non-contractile tails) Lambdavirus Escherichia phage lambda (Bacteriophage lambda) |
| Enzyme Sequence | MKTPTIPTLLGPDGMTSLREYAGYHGGGSGFGGQLRSWNPPSESVDAALLPNFTRGNARADDLVRNNGYAANAIQLHQDHIVGSFFRLSHRPSWRYLGIGEEEARAFSREVEAAWKEFAEDDCCCIDVERKRTFTMMIREGVAMHAFNGELFVQATWDTSSSRLFRTQFRMVSPKRISNPNNTGDSRNCRAGVQINDSGAALGYYVSEDGYPGWMPQKWTWIPRELPGGRASFIHVFEPVEDGQTRGANVFYSVMEQMKMLDTLQNTQLQSAIVKAMYAATIESELDTQSAMDFILGANSQEQRERLTGWIGEIAAYYAAAPVRLGGAKVPHLMPGDSLNLQTAQDTDNGYSVFEQSLLRYIAAGLGVSYEQLSRNYAQMSYSTARASANESWAYFMGRRKFVASRQASQMFLCWLEEAIVRRVVTLPSKARFSFQEARSAWGNCDWIGSGRMAIDGLKEVQEAVMLIEAGLSTYEKECAKRGDDYQEIFAQQVRETMERRAAGLKPPAWAAAAFESGLRQSTEEEKSDSRAA |
| Enzyme Length | 533 |
| Uniprot Accession Number | P03710 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: Forms the portal vertex of the capsid (PubMed:6228056, PubMed:6232391). This portal plays critical roles in head assembly, genome packaging, neck/tail attachment, and genome ejection (Probable). The portal protein multimerizes as a single ring-shaped homododecamer arranged around a central channel (PubMed:6232391). Binds to the terminase subunits to form the packaging machine (PubMed:7799432). {ECO:0000255|HAMAP-Rule:MF_04135, ECO:0000269|PubMed:6228056, ECO:0000269|PubMed:6232391, ECO:0000269|PubMed:7799432, ECO:0000305}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (2); Site (1) |
| Keywords | Capsid protein;DNA-binding;Reference proteome;Viral capsid assembly;Viral genome ejection through host cell envelope;Viral genome packaging;Viral long flexible tail ejection system;Viral penetration into host cytoplasm;Viral release from host cell;Virion;Virus entry into host cell |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Virion {ECO:0000255|HAMAP-Rule:MF_04135, ECO:0000269|PubMed:6228056}. |
| Modified Residue | |
| Post Translational Modification | PTM: Proteolytically cleaved by the viral protease during capsid maturation. {ECO:0000255|HAMAP-Rule:MF_04135, ECO:0000269|PubMed:20620152}. |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 59,466 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |