| IED ID | IndEnz0002007995 |
| Enzyme Type ID | protease007995 |
| Protein Name |
Calcium-dependent protease EC 3.4.21.- Trypsin |
| Gene Name | prcA Ava_4009 |
| Organism | Trichormus variabilis (strain ATCC 29413 / PCC 7937) (Anabaena variabilis) |
| Taxonomic Lineage | cellular organisms Bacteria Terrabacteria group Cyanobacteria/Melainabacteria group Cyanobacteria Nostocales Nostocaceae Trichormus Anabaena variabilis Trichormus variabilis (strain ATCC 29413 / PCC 7937) (Anabaena variabilis) |
| Enzyme Sequence | MVHVRYGGQNGEQYELAISENHIVVRTESRSSLISDRPFEAAPVSPQARNILNQFELSTRFSQAGVEVLHVKEPSHDGALRDTAREILNQEPEVQFAGRVLIDPVSQQPIVYTENLFVKFDHEEDVSFCQEILGRYGLTIKRQLEYARNAYFVSAPSNTGLAIFDISERLLNEESVELCHPELVREFRQRQAFPPQWHLKQTTIGGKTINAHANVEAAWKLSDGTGTIIAIIDDGVDIDHEEFRSSGKIVAPRDVTRKTNFPTPGNRDNHGTACAGVACGNGNFGASGVAPGAKLMPIRFVSALGSQDEADSFVWAAQNGADVISCSWGPPDGTWWDDKDPLHKQKVPLPDSTRLAMDYAINKGRNGKGCVILFAAGNGNESVDNDGYASYEKVIAVAACNDFGTRSAYSDFGTAVWCAFPSNNGNPSQTPGIWTADRTGVVGYNSGNTNLGDQAGNYTNSFGGTSSACPGAAGVAALILSRNPNLRWDEVRDIIKRSCDRIDPVGGNYNAEGRSPFYGYGRINALKAVELALPAQPEPVSIFTAVQDVPINDLQISQLSLAIANTNPIKSIKVTVDIEHTYIGDLVVSLNPPAESGVLPIILHDRKGGGADDIKQTYDEVSTPGLTALKGKIPQGTWTLEVADKAQADTGKIRSLTIELGF |
| Enzyme Length | 662 |
| Uniprot Accession Number | P23916 |
| Absorption | |
| Active Site | ACT_SITE 233; /note=Charge relay system; /evidence=ECO:0000255|PROSITE-ProRule:PRU01240; ACT_SITE 270; /note=Charge relay system; /evidence=ECO:0000255|PROSITE-ProRule:PRU01240; ACT_SITE 466; /note=Charge relay system; /evidence=ECO:0000255|PROSITE-ProRule:PRU01240 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.21.- |
| Enzyme Function | FUNCTION: Degrades phycobiliproteins in vitro. Has a substrate specificity similar to that of trypsin. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (1); Domain (2); Frameshift (1); Propeptide (1); Sequence conflict (1) |
| Keywords | Calcium;Cytoplasm;Direct protein sequencing;Hydrolase;Protease;Serine protease;Zymogen |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:8944762}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 71,598 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |