Detail Information for IndEnz0002008011
IED ID IndEnz0002008011
Enzyme Type ID protease008011
Protein Name Proctolin
Gene Name
Organism Periplaneta americana (American cockroach) (Blatta americana)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Panarthropoda Arthropoda Mandibulata Pancrustacea Hexapoda Insecta Dicondylia Pterygota (winged insects) Neoptera Polyneoptera Dictyoptera Blattodea (cockroaches) Blattoidea Blattidae (American cockroach family) Blattinae Periplaneta Periplaneta americana (American cockroach) (Blatta americana)
Enzyme Sequence RYLPT
Enzyme Length 5
Uniprot Accession Number P67859
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Stimulates cardiac output and hindgut motility, modulates visceral and skeletal muscle in many arthropods. Also inhibits activities of the human peptidase neprilysin (NEP/MME) (PubMed:26056922). {ECO:0000269|PubMed:26056922}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Peptide (1)
Keywords Direct protein sequencing;Hydrolase;Neuropeptide;Protease;Secreted;Serine protease
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Secreted.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 649
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda