IED ID |
IndEnz0002008011 |
Enzyme Type ID |
protease008011 |
Protein Name |
Proctolin
|
Gene Name |
|
Organism |
Periplaneta americana (American cockroach) (Blatta americana) |
Taxonomic Lineage |
cellular organisms
Eukaryota
Opisthokonta
Metazoa
Eumetazoa
Bilateria
Protostomia
Ecdysozoa
Panarthropoda
Arthropoda
Mandibulata
Pancrustacea
Hexapoda
Insecta
Dicondylia
Pterygota (winged insects)
Neoptera
Polyneoptera
Dictyoptera
Blattodea (cockroaches)
Blattoidea
Blattidae (American cockroach family)
Blattinae
Periplaneta
Periplaneta americana (American cockroach) (Blatta americana)
|
Enzyme Sequence |
RYLPT |
Enzyme Length |
5 |
Uniprot Accession Number |
P67859 |
Absorption |
|
Active Site |
|
Activity Regulation |
|
Binding Site |
|
Calcium Binding |
|
catalytic Activity |
|
DNA Binding |
|
EC Number |
|
Enzyme Function |
FUNCTION: Stimulates cardiac output and hindgut motility, modulates visceral and skeletal muscle in many arthropods. Also inhibits activities of the human peptidase neprilysin (NEP/MME) (PubMed:26056922). {ECO:0000269|PubMed:26056922}. |
Temperature Dependency |
|
PH Dependency |
|
Pathway |
|
nucleotide Binding |
|
Features |
Peptide (1) |
Keywords |
Direct protein sequencing;Hydrolase;Neuropeptide;Protease;Secreted;Serine protease |
Interact With |
|
Induction |
|
Subcellular Location |
SUBCELLULAR LOCATION: Secreted. |
Modified Residue |
|
Post Translational Modification |
|
Signal Peptide |
|
Structure 3D |
|
Cross Reference PDB |
- |
Mapped Pubmed ID |
- |
Motif |
|
Gene Encoded By |
|
Mass |
649 |
Kinetics |
|
Metal Binding |
|
Rhea ID |
|
Cross Reference Brenda |
|