| IED ID | IndEnz0002008044 |
| Enzyme Type ID | protease008044 |
| Protein Name |
Packaging protein 3 L1-52/55 kDa protein Packaging protein 52K |
| Gene Name | L1 |
| Organism | Canine adenovirus serotype 1 (strain RI261) (CAdV-1) (Canine adenovirus 1 (strain RI261)) |
| Taxonomic Lineage | Viruses Varidnaviria Bamfordvirae Preplasmiviricota Tectiliviricetes Rowavirales Adenoviridae Mastadenovirus Canine mastadenovirus A Canine adenovirus 1 Canine adenovirus serotype 1 (strain RI261) (CAdV-1) (Canine adenovirus 1 (strain RI261)) |
| Enzyme Sequence | MHPVLRQMKPLPASVVKLEAESEGLARLQGGAAPEVHPRVQMKQEAAEAYIPASNVFRDNEGEEAEGLRHLKYESGRMLRKDHPSKRVLDERDFEKSPENGISAAEAHLKSADLVTAYEHTVKAEVNFQTTFNNNVRTLIAREEVVIGLMHLWDFVEAFLENPVSKALTAQLFLIVQHCRDEGVLRESLLNIAEPESRWLVDLLNLLQTIVVQERSLAVGEKVAAINYSVITLSKHYARKIFNSVFVPIDKEAKINTFYMRTVVQILVLSDDLGMYRNERIERAVSGARQRELNDRELMYRLREALTSNGLSEIEGGEDSARVRSKENWGAGAGVGAASARYPHLLDYEEKENPDGSVSFQQHERGTQSHENGGHAEPAYSRRQLGRFY |
| Enzyme Length | 389 |
| Uniprot Accession Number | P68973 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: Involved in viral genome packaging through its interaction with packaging proteins 1 and 2. After proteolytic cleavage by adenovirus protease, L1 52/55k protein is removed from the capsid during viral maturation. {ECO:0000255|HAMAP-Rule:MF_04058}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Erroneous initiation (1); Region (2) |
| Keywords | Host nucleus;Late protein;Phosphoprotein;Viral genome packaging;Viral release from host cell |
| Interact With | |
| Induction | INDUCTION: Expressed in the early phase and late phase of the viral replicative cycle. {ECO:0000255|HAMAP-Rule:MF_04058}. |
| Subcellular Location | SUBCELLULAR LOCATION: Host nucleus {ECO:0000255|HAMAP-Rule:MF_04058}. Note=Nuclear protein present in empty capsids and assembly intermediates. {ECO:0000255|HAMAP-Rule:MF_04058}. |
| Modified Residue | |
| Post Translational Modification | PTM: Cleaved at different sites by the viral protease during virion maturation. {ECO:0000255|HAMAP-Rule:MF_04058}. |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 43,901 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |