| IED ID | IndEnz0002008120 |
| Enzyme Type ID | protease008120 |
| Protein Name |
Carboxypeptidase SOL1 EC 3.4.17.- Protein SUPPRESSOR OF LLP1 1 |
| Gene Name | SOL1 At1g71696 F14O23.7 F26A9.4 |
| Organism | Arabidopsis thaliana (Mouse-ear cress) |
| Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae rosids malvids Brassicales Brassicaceae Camelineae Arabidopsis Arabidopsis thaliana (Mouse-ear cress) |
| Enzyme Sequence | MSKLRFFQSLLISTVICFFLPSINARGGHSDHIHPGDGNYSFHGIVRHLFAQEEPTPSLELTRGYMTNDDLEKAMKDFTKRCSKISRLYSIGKSVNGFPLWVIEISDRPGEIEAEPAFKYIGNVHGDEPVGRELLLRLANWICDNYKKDPLAQMIVENVHLHIMPSLNPDGFSIRKRNNANNVDLNRDFPDQFFPFNDDLNLRQPETKAIMTWLRDIRFTASATLHGGALVANFPWDGTEDKRKYYYACPDDETFRFLARIYSKSHRNMSLSKEFEEGITNGASWYPIYGGMQDWNYIYGGCFELTLEISDNKWPKASELSTIWDYNRKSMLNLVASLVKTGVHGRIFSLDKGKPLPGLVVVKGINYTVKAHQTYADYHRLLVPGQKYEVTASSPGYKSKTTTVWLGENAVTADFILIPETSSRGNQLRSSCDCSCKSCGQPLLTQFFTETNNGITLTLFVVVVFLCFLLQRRVRFNLWKQRQSSRRSITV |
| Enzyme Length | 491 |
| Uniprot Accession Number | Q9M9H7 |
| Absorption | |
| Active Site | ACT_SITE 308; /note=Nucleophile; /evidence=ECO:0000305|PubMed:12932329 |
| Activity Regulation | |
| Binding Site | BINDING 286; /note=Substrate; /evidence=ECO:0000250|UniProtKB:P15085 |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.17.- |
| Enzyme Function | FUNCTION: Possesses in vitro carboxypeptidase activity against the C-terminal arginine and lysine residues. Involved in the maturation of CLE19. Removes the C-terminal arginine residue of CLE19 proprotein. The cleavage of the C-terminal arginine residue is necessary for CLE19 activity in vivo. Is not involved in generating active CLV3 (PubMed:24118638). Is not involved in CLE19 or CLV3 perception (PubMed:12932329, PubMed:24118638). {ECO:0000269|PubMed:12932329, ECO:0000269|PubMed:24118638}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (1); Binding site (1); Chain (1); Erroneous gene model prediction (1); Glycosylation (2); Metal binding (3); Region (2); Signal peptide (1); Topological domain (2); Transmembrane (1) |
| Keywords | Alternative splicing;Carboxypeptidase;Endosome;Glycoprotein;Hydrolase;Membrane;Metal-binding;Protease;Reference proteome;Signal;Transmembrane;Transmembrane helix;Zinc |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Endosome membrane {ECO:0000269|PubMed:24118638}; Single-pass type I membrane protein {ECO:0000255}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..25; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 30665887; |
| Motif | |
| Gene Encoded By | |
| Mass | 56,046 |
| Kinetics | |
| Metal Binding | METAL 125; /note=Zinc; catalytic; /evidence=ECO:0000250|UniProtKB:P15085; METAL 128; /note=Zinc; catalytic; /evidence=ECO:0000250|UniProtKB:P15085; METAL 226; /note=Zinc; catalytic; /evidence=ECO:0000250|UniProtKB:P15085 |
| Rhea ID | |
| Cross Reference Brenda |