| IED ID |
IndEnz0002008144 |
| Enzyme Type ID |
protease008144 |
| Protein Name |
Nisin biosynthesis regulatory protein NisR
|
| Gene Name |
nisR |
| Organism |
Lactococcus lactis subsp. lactis (Streptococcus lactis) |
| Taxonomic Lineage |
cellular organisms
Bacteria
Terrabacteria group
Firmicutes
Bacilli
Lactobacillales
Streptococcaceae
Lactococcus (lactic streptococci)
Lactococcus lactis
Lactococcus lactis subsp. lactis (Streptococcus lactis)
|
| Enzyme Sequence |
MVYKILIVDDDQEILKLMKTALEMRNYEVATHQNISLPLDITDFQGFDLILLDIMMSNIEGTEICKRIRREISTPIIFVSAKDTEEDIINGLGIGGDDYITKPFSLKQLVAKVEANIKREERNKHAVHVFSEIRRDLGPITFYLEERRVCVNGQTIPLTCREYDILELLSQRTSKVYTREDIYDDVYDEYSNALFRSISEYIYQIRSKFAPYDINPIKTVRGLGYQWHG |
| Enzyme Length |
229 |
| Uniprot Accession Number |
Q07597 |
| Absorption |
|
| Active Site |
|
| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
DNA_BIND 132..229; /note=OmpR/PhoB-type; /evidence=ECO:0000255|PROSITE-ProRule:PRU01091 |
| EC Number |
|
| Enzyme Function |
FUNCTION: Member of the two-component regulatory system NisK/NisR involved in the regulation of the biosynthesis of lantibiotic nisin. NisR may function as a regulatory protein. |
| Temperature Dependency |
|
| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
|
| Features |
Chain (1); DNA binding (1); Domain (1); Modified residue (1); Sequence conflict (1) |
| Keywords |
Activator;DNA-binding;Phosphoprotein;Transcription;Transcription regulation;Two-component regulatory system |
| Interact With |
|
| Induction |
|
| Subcellular Location |
|
| Modified Residue |
MOD_RES 53; /note=4-aspartylphosphate; /evidence=ECO:0000255|PROSITE-ProRule:PRU00169 |
| Post Translational Modification |
PTM: Phosphorylated by NisK. {ECO:0000305}. |
| Signal Peptide |
|
| Structure 3D |
|
| Cross Reference PDB |
- |
| Mapped Pubmed ID |
- |
| Motif |
|
| Gene Encoded By |
|
| Mass |
26,715 |
| Kinetics |
|
| Metal Binding |
|
| Rhea ID |
|
| Cross Reference Brenda |
|