| IED ID | IndEnz0002008159 |
| Enzyme Type ID | protease008159 |
| Protein Name |
Pregnancy-associated glycoprotein PAG EC 3.4.23.- |
| Gene Name | PAG |
| Organism | Equus caballus (Horse) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Laurasiatheria Perissodactyla (odd-toed ungulates) Equidae (horses) Equus Equus Equus caballus (Horse) |
| Enzyme Sequence | MKWFGVLGLVTLSECLVTIPLVKIKSLRENLREKDMLKEYLEKYPFRLTHKLLHKHADSGVAFEPMRNYLDIAYMGIISVGTPPQEFQVIFDTGSADLWVPSIYCSSPACSNHNTFNPLRSSTFVASGQPIKLIYGTGKMSGFVGYDTIKISSLVDRNQAFGLSVEEPDKILELATFDGILGLSYPSLSVKGVTPVFDNLWNQGLLSQKLFAFYLSRKGKKGSVVMFGGVDPSYYTGELHWVPVSKPLYWQISMDSISINGKVIACDGGCQAIVDTGTSLLLGPQDAVLNIQEIIQARRSTSGEYFIDCDAVNTLPDILFTIDGIGYPVPANAYIQKDAALGICFSSFEGNEDISNNSEEWILGDVFLRLYFTVFDRENDRIGLATAV |
| Enzyme Length | 388 |
| Uniprot Accession Number | Q28389 |
| Absorption | |
| Active Site | ACT_SITE 92; /evidence=ECO:0000255|PROSITE-ProRule:PRU10094; ACT_SITE 275; /evidence=ECO:0000255|PROSITE-ProRule:PRU10094 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.23.- |
| Enzyme Function | |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (2); Chain (1); Disulfide bond (3); Domain (1); Glycosylation (1); Propeptide (1); Signal peptide (1) |
| Keywords | Aspartyl protease;Disulfide bond;Glycoprotein;Hydrolase;Protease;Reference proteome;Secreted;Signal;Zymogen |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted, extracellular space. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..15; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 42,891 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |