| IED ID | IndEnz0002008166 |
| Enzyme Type ID | protease008166 |
| Protein Name |
Calpain-like protease palB/RIM13 EC 3.4.22.- Cysteine protease palB |
| Gene Name | palB palBory AO090005000756 |
| Organism | Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Eurotiales (green and blue molds) Aspergillaceae Aspergillus Aspergillus subgen. Circumdati Aspergillus oryzae (Yellow koji mold) Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold) |
| Enzyme Sequence | MSRPNASAQKSFITQALKAERDVSSATSQRQALEAAIDAAEHYMKALNLASVQKDKHALDAKCKEWLTRAEKIKESKDWQAAARFHDKTVPEPRLPVSTRKLTTREEIILLEGAKLNGFIFPPWSTSPGSDEFKREDGESPFTDKPDLHLSYPQRKVFDGWKRPSELLAKDTEDVYTKVVPVMSVPGKTDLVQDMLTDCSVVASLCATTSMLERGQCTHFLPMIYPSRGSSQPSPSGKYIFRFYFNGCFRKVIIDDRLPSSKTSRSLHVIDRKNPNFLWPALVEKAYLKLRGGYDFPGSNSGTDLWVLTGWIPEQVFLHNDDVTGDQLWKRLYRSFHQGDVLLTIGTGELTEREQRELGLVSEHDYAILDMKESKGRRQLLVKNPWAGADTAPGDNGSLSASQDLPHNPPSFEPGTFWMDCEKLLQHFENLYLNWNPEIFKYREDVHFTWDLNNGRGVAGCFVNNPQFAVSTENGGIVWLLLGKHFRTTGQPERPLDEYQANEESAFISIYVFNADGKRVSLSDGALHRGPYVDSPNTLMRLEMPPRTTYTVVVSEQSLPSLNQNFTLSAFSTCPVRMAKAQDKYMCVRKIQGSWTPSTAGGNAESSRYPLNPQFRLEIENDTDVSLLLECPNTELATHVKLFWSNGNRVSRVRSRDIIADSGDYRRGGSLVEKKALEPGSYTIVCSTFAPDQLGRFTLWVSSLVPCKTSPLPPEAAGRRTVISDIGVLPPGRDRMLASLQVPRLTRIKLITRSRQSIIGSHPVGPSPVLMTVELGQGPYKQILATSEDGTHSDAVSGVRVEDFDLQPGLEESGGIWIVIERIGGPGGQVEDHFEVEALAEERVEIGEWILEDA |
| Enzyme Length | 854 |
| Uniprot Accession Number | Q9Y6Z8 |
| Absorption | |
| Active Site | ACT_SITE 199; /evidence=ECO:0000255|PROSITE-ProRule:PRU00239; ACT_SITE 364; /evidence=ECO:0000255|PROSITE-ProRule:PRU00239; ACT_SITE 384; /evidence=ECO:0000255|PROSITE-ProRule:PRU00239 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.22.- |
| Enzyme Function | FUNCTION: Required for the proteolytic cleavage of the transcription factor pacC in response to alkaline ambient pH. Probably is the signaling protease that mediates the first proteolytic cleavage within the signaling protease box of pacC (By similarity). {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (1); Domain (2); Sequence conflict (1) |
| Keywords | Hydrolase;Protease;Reference proteome;Thiol protease |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 95,470 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |