| IED ID |
IndEnz0002008348 |
| Enzyme Type ID |
protease008348 |
| Protein Name |
pH-response transcription factor pacC/RIM101
|
| Gene Name |
PAC1 |
| Organism |
Gibberella moniliformis (Maize ear and stalk rot fungus) (Fusarium verticillioides) |
| Taxonomic Lineage |
cellular organisms
Eukaryota
Opisthokonta
Fungi
Dikarya
Ascomycota
saccharomyceta
Pezizomycotina
leotiomyceta
sordariomyceta
Sordariomycetes
Hypocreomycetidae
Hypocreales
Nectriaceae
Fusarium
Fusarium fujikuroi species complex
Gibberella moniliformis (Maize ear and stalk rot fungus) (Fusarium verticillioides)
|
| Enzyme Sequence |
MSPSAPEQKPQLQQQQQQQQQGSSSGDSSSGSVNDSKSVTPAPSATSSTSQSSTAPSTSSDDNLICRWNACNQKFPAPEALYEHICERHVGRKSTNNLNLTCQWNSCRTTTVKRDHITSHIRVHVPLKPHKCEFCGKSFKRPQDLKKHVKTHADDSVLVRPSQDPQGGLNYRPQPPKGPSSYYDHTGQMRTNAAAFAHQAGHPSGGYYAPQPSTNYGLYFNQPPINNARTEHLGYSAAAGGYDRKRTYDMVDDFFGSAKRRQIDPSSYAQIGRSLMPLHGNLSVPNGPMTATEQYMPQPAPAPVHAGPTPSQNPLAQQYYLPMPSARTQKDLIHIDTILGQMQDTIYENANHATAGVHIHHAENGFNGYRNTPSPPTSHRSPTGMHVGADGYQPVSAASMASPMTAISSTGTPAVTPPSSSMSYTSGHSPSPSSSAMSPQSRHGSTASVMYPTLPTSLPAVSQGFGHSATTTLGPSFDGSERRRYSGGMLQRARAGPLPLPHEDTSGASTPKASESALSVGSPSSESDVSDATREREEQYDRWLENMRVIETLREYVRGRLERKEFVEDNESPQSSHSDAMDVDPKSPQAPPRELGTPREGSSLYPILRMPGA |
| Enzyme Length |
613 |
| Uniprot Accession Number |
Q873X0 |
| Absorption |
|
| Active Site |
|
| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
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| Enzyme Function |
FUNCTION: Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH. At alkaline ambient pH, activates transcription of alkaline-expressed genes (including PAC1 itself) and represses transcription of acid-expressed genes (By similarity). {ECO:0000250}. |
| Temperature Dependency |
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| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
|
| Features |
Chain (1); Compositional bias (2); Motif (2); Region (5); Zinc finger (3) |
| Keywords |
Activator;Cytoplasm;DNA-binding;Metal-binding;Nucleus;Repeat;Repressor;Transcription;Transcription regulation;Zinc;Zinc-finger |
| Interact With |
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| Induction |
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| Subcellular Location |
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
| Modified Residue |
|
| Post Translational Modification |
PTM: Activated by C-terminal proteolytic cleavage by signaling protease (probably palB/RIM13) at neutral to alkaline ambient pH. {ECO:0000250}. |
| Signal Peptide |
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| Structure 3D |
|
| Cross Reference PDB |
- |
| Mapped Pubmed ID |
- |
| Motif |
MOTIF 451..454; /note=YPX[LI] motif 1; MOTIF 605..608; /note=YPX[LI] motif 2 |
| Gene Encoded By |
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| Mass |
66,373 |
| Kinetics |
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| Metal Binding |
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| Rhea ID |
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| Cross Reference Brenda |
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