| IED ID | IndEnz0002008464 |
| Enzyme Type ID | protease008464 |
| Protein Name |
Putative signal peptide peptidase SppA EC 3.4.21.- |
| Gene Name | sppA BH3198 |
| Organism | Alkalihalobacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) (Bacillus halodurans) |
| Taxonomic Lineage | cellular organisms Bacteria Terrabacteria group Firmicutes Bacilli Bacillales Bacillaceae Alkalihalobacillus Alkalihalobacillus halodurans (Bacillus halodurans) Alkalihalobacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) (Bacillus halodurans) |
| Enzyme Sequence | MMSRKRWLALIAAAMLFVASAAISLVSSPAVDVDEWVGTGTSYKQTIVETGTDFGKSIAILELSGVIQDTGSAPSLLNTGVYHHRDFLKQLEKAGEDPNIAGIILQVNTPGGGVLESAEIHKQVEEIVQDSEKPVYVSMGNMAASGGYYISAPATKIYAHPQTITGSIGVIMQSIDISGLAENLGIEFNTFKSGPYKDILSQTREVTDEEEDILQTLVDEMYDEFVRVIVDGRGMSETEVRELADGRIYTGSQAVATGLVDELGGLDDVIESMKEDLGADYNVIRYEHSLGLYDFFSMSTNRLLSPSYELQSIERLLNQSNTPTLQYLYAE |
| Enzyme Length | 331 |
| Uniprot Accession Number | Q9K809 |
| Absorption | |
| Active Site | ACT_SITE 145; /note=Nucleophile; /evidence=ECO:0000250; ACT_SITE 197; /note=Proton donor/acceptor; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.21.- |
| Enzyme Function | FUNCTION: Digestion of the cleaved signal peptides. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (2); Chain (1); Transmembrane (1) |
| Keywords | Cell membrane;Hydrolase;Membrane;Protease;Reference proteome;Serine protease;Transmembrane;Transmembrane helix |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 36,104 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |