| IED ID | IndEnz0002008472 |
| Enzyme Type ID | protease008472 |
| Protein Name |
Putative signal peptide peptidase SppA EC 3.4.21.- |
| Gene Name | sppA |
| Organism | Enterococcus faecium (Streptococcus faecium) |
| Taxonomic Lineage | cellular organisms Bacteria Terrabacteria group Firmicutes Bacilli Lactobacillales Enterococcaceae Enterococcus Enterococcus faecium (Streptococcus faecium) |
| Enzyme Sequence | MNKRRWIAVGVACGLLLLSIIVALIPGKDKEEASNTTLTGINKIFYGSNEITEETLEEGASNKKIVKLSVNGVIADTGESNLFSREQYNHQNFLTQLKKIQEDKAVKGVLLEVNSPGGGIYESAEIAKEMAKIKKLDIPIYTAFKNTAASGGYYISAGSDKIFATEETTTGSIGVIISGLNYSGLLEKLGVTDATYKSGALKDMMSPQHKPSEEENKVIQEFVMSAYDRFVNVVAKGRNMDTNAVKELADGRIYDGNQAVENGLVDQIGYSEDALDSLKKEKKLTDATVIEYKNDTTGFASSWLGNKIAEWQGLKATTSDRVISVFEKLGFSDTPKPMYYYGGL |
| Enzyme Length | 344 |
| Uniprot Accession Number | Q9X480 |
| Absorption | |
| Active Site | ACT_SITE 150; /note=Nucleophile; /evidence=ECO:0000250; ACT_SITE 202; /note=Proton donor/acceptor; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.21.- |
| Enzyme Function | FUNCTION: Digestion of the cleaved signal peptides. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (2); Chain (1); Transmembrane (1) |
| Keywords | Cell membrane;Hydrolase;Membrane;Protease;Serine protease;Transmembrane;Transmembrane helix |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 37,543 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |