| IED ID |
IndEnz0002008602 |
| Enzyme Type ID |
protease008602 |
| Protein Name |
Putative zinc metalloprotease Rip3
|
| Gene Name |
rip3 Rv2625c |
| Organism |
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
| Taxonomic Lineage |
cellular organisms
Bacteria
Terrabacteria group
Actinobacteria
Actinomycetia (high G+C Gram-positive bacteria)
Corynebacteriales
Mycobacteriaceae
Mycobacterium
Mycobacterium tuberculosis complex
Mycobacterium tuberculosis
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
|
| Enzyme Sequence |
MRDAIPLGRIAGFVVNVHWSVLVILWLFTWSLATMLPGTVGGYPAVVYWLLGAGGAVMLLASLLAHELAHAVVARRAGVSVESVTLWLFGGVTALGGEAKTPKAAFRIAFAGPATSLALSATFGALAITLAGVRTPAIVISVAWWLATVNLLLGLFNLLPGAPLDGGRLVRAYLWRRHGDSVRAGIGAARAGRVVALVLIALGLAEFVAGGLVGGVWLAFIGWFIFAAAREEETRISTQQLFAGVRVADAMTAQPHTAPGWINVEDFIQRYVLGERHSAYPVADRDGSITGLVALRQLRDVAPSRRSTTSVGDIALPLHSVPTARPQEPLTALLERMAPLGPRSRALVTEGSAVVGIVTPSDVARLIDVYRLAQPEPTFTTSPQDADRFSDAG |
| Enzyme Length |
393 |
| Uniprot Accession Number |
P9WHR1 |
| Absorption |
|
| Active Site |
ACT_SITE 67; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095 |
| Activity Regulation |
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| Binding Site |
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| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
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| EC Number |
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| Enzyme Function |
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| Temperature Dependency |
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| PH Dependency |
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| Pathway |
|
| nucleotide Binding |
|
| Features |
Active site (1); Chain (1); Domain (2); Metal binding (2); Transmembrane (6) |
| Keywords |
CBS domain;Cell membrane;Hydrolase;Membrane;Metal-binding;Metalloprotease;Protease;Reference proteome;Repeat;Transmembrane;Transmembrane helix;Zinc |
| Interact With |
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| Induction |
INDUCTION: A member of the dormancy regulon. Induced in response to reduced oxygen tension (hypoxia), low levels of nitric oxide (NO) and carbon monoxide (CO). It is hoped that this regulon will give insight into the latent, or dormant phase of infection. {ECO:0000269|PubMed:11416222, ECO:0000269|PubMed:12953092, ECO:0000269|PubMed:18400743}. |
| Subcellular Location |
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
| Modified Residue |
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| Post Translational Modification |
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| Signal Peptide |
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| Structure 3D |
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| Cross Reference PDB |
- |
| Mapped Pubmed ID |
- |
| Motif |
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| Gene Encoded By |
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| Mass |
41,480 |
| Kinetics |
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| Metal Binding |
METAL 66; /note=Zinc; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095; METAL 70; /note=Zinc; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095 |
| Rhea ID |
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| Cross Reference Brenda |
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