| IED ID |
IndEnz0002008627 |
| Enzyme Type ID |
protease008627 |
| Protein Name |
26S proteasome regulatory subunit RPN11
|
| Gene Name |
RPN11 CAGL0L09152g |
| Organism |
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata) |
| Taxonomic Lineage |
cellular organisms
Eukaryota
Opisthokonta
Fungi
Dikarya
Ascomycota
saccharomyceta
Saccharomycotina (true yeasts)
Saccharomycetes
Saccharomycetales
Saccharomycetaceae
Nakaseomyces
Nakaseomyces/Candida clade
Candida glabrata (Yeast) (Torulopsis glabrata)
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)
|
| Enzyme Sequence |
MERLQRLMMNTKVGAADANKDDTKETVYISSIALLKMLKHGRAGVPMEVMGLMLGEFVDEYTVNVVDVFAMPQSGTGVSVEAVDDVFQARMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNNRAVAVVVDPIQSVKGKVVIDAFRLIDTGALINNQEPRQTTSNSGLMNKANIQALIHGLNRHYYSLNIDYHKTPAETKMLLNLHKEQWQSGLKMQDYQEKETENLEATKRMVAVAQQYSKRIEEEKELSEEELKTRYVGKQDPKKHLAKTAENTLEENTVSVLTAGVNSIAIK |
| Enzyme Length |
306 |
| Uniprot Accession Number |
Q6FKS1 |
| Absorption |
|
| Active Site |
|
| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
|
| Enzyme Function |
FUNCTION: Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. {ECO:0000250}. |
| Temperature Dependency |
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| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
|
| Features |
Chain (1); Domain (1); Metal binding (3); Motif (1) |
| Keywords |
Hydrolase;Metal-binding;Metalloprotease;Protease;Proteasome;Reference proteome;Zinc |
| Interact With |
|
| Induction |
|
| Subcellular Location |
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| Modified Residue |
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| Post Translational Modification |
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| Signal Peptide |
|
| Structure 3D |
|
| Cross Reference PDB |
- |
| Mapped Pubmed ID |
- |
| Motif |
MOTIF 109..122; /note=JAMM motif; /evidence=ECO:0000255|PROSITE-ProRule:PRU01182 |
| Gene Encoded By |
|
| Mass |
34,424 |
| Kinetics |
|
| Metal Binding |
METAL 109; /note=Zinc; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU01182; METAL 111; /note=Zinc; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU01182; METAL 122; /note=Zinc; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU01182 |
| Rhea ID |
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| Cross Reference Brenda |
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