IED ID | IndEnz0002008677 |
Enzyme Type ID | protease008677 |
Protein Name |
26S proteasome regulatory subunit S10B homolog B 26S proteasome AAA-ATPase subunit RPT4b 26S proteasome subunit S10B homolog B Regulatory particle triple-A ATPase subunit 4b |
Gene Name | RPT4B At1g45000 F27F5.8 |
Organism | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae rosids malvids Brassicales Brassicaceae Camelineae Arabidopsis Arabidopsis thaliana (Mouse-ear cress) |
Enzyme Sequence | MSDGDDAARRRTAAVTDYRKKLLHHKELESRVRTARENLRAAKKEFNKTEDDLKSLQSVGQIIGEVLRPLDNERLIVKASSGPRYVVGCRSKVDKEKLTSGTRVVLDMTTLTIMRALPREVDPVVYNMLHEDPGNISYSAVGGLGDQIRELRESIELPLMNPELFLRVGIKPPKGVLLYGPPGTGKTLLARAIASNIDANFLKVVSSAIIDKYIGESARLIREMFNYAREHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQLDGFDQLGKVKMIMATNRPDVLDPALLRPGRLDRKIEIPLPNEQSRMEILKIHASGIAKHGEIDYEAIVKLGEGFNGADLRNICTEAGMFAIRAERDYVIHEDFMKAVRKLSEAKKLESSSHYNADFGKE |
Enzyme Length | 399 |
Uniprot Accession Number | Q9MAK9 |
Absorption | |
Active Site | |
Activity Regulation | |
Binding Site | |
Calcium Binding | |
catalytic Activity | |
DNA Binding | |
EC Number | |
Enzyme Function | FUNCTION: The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. |
Temperature Dependency | |
PH Dependency | |
Pathway | |
nucleotide Binding | NP_BIND 180..187; /note=ATP; /evidence=ECO:0000255 |
Features | Chain (1); Cross-link (1); Nucleotide binding (1) |
Keywords | ATP-binding;Alternative splicing;Cytoplasm;Isopeptide bond;Nucleotide-binding;Nucleus;Proteasome;Reference proteome;Ubl conjugation |
Interact With | |
Induction | |
Subcellular Location | SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
Modified Residue | |
Post Translational Modification | |
Signal Peptide | |
Structure 3D | |
Cross Reference PDB | - |
Mapped Pubmed ID | 15496452; 16287169; 17317660; 17432890; 17825468; 20118269; 20706207; 21166475; 21798944; |
Motif | |
Gene Encoded By | |
Mass | 44,756 |
Kinetics | |
Metal Binding | |
Rhea ID | |
Cross Reference Brenda |