| IED ID | IndEnz0002008746 |
| Enzyme Type ID | protease008746 |
| Protein Name |
Serine protease SP24D EC 3.4.21.- AgSp24D |
| Gene Name | Sp24D AGAP006416 |
| Organism | Anopheles gambiae (African malaria mosquito) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Panarthropoda Arthropoda Mandibulata Pancrustacea Hexapoda Insecta Dicondylia Pterygota (winged insects) Neoptera Endopterygota Diptera Nematocera Culicomorpha Culicoidea Culicidae (mosquitos) Anophelinae Anopheles Cellia Pyretophorus gambiae species complex Anopheles gambiae (African malaria mosquito) |
| Enzyme Sequence | MTLADRVPLALAALAYLALVSGVRFHLSEQNDVLPGGSQARRPFFQGARIVGGSVASEGQFPHQVALLRGNALTCGGSLIESRWVLTAAHCVYNGALVVPASSIVVVAGSVSLSNGVRRAVARVIPHERYGNFKNDVALLQLQLSLPSSAYIRPIALRTTSVPAGSEVVISGWGRMYQGGPVSNMLRYNRATVVADQQCRMATGISTGLICFTSPVNNGACNGDSGGPAILNNQLVGVANFIINYCGSASPDGYARVSDFVTWIQTTMRRY |
| Enzyme Length | 271 |
| Uniprot Accession Number | Q17004 |
| Absorption | |
| Active Site | ACT_SITE 90; /note=Charge relay system; /evidence=ECO:0000250; ACT_SITE 136; /note=Charge relay system; /evidence=ECO:0000250; ACT_SITE 225; /note=Charge relay system; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.21.- |
| Enzyme Function | |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (1); Disulfide bond (3); Domain (1); Frameshift (1); Propeptide (1); Sequence conflict (5); Signal peptide (1) |
| Keywords | Disulfide bond;Hydrolase;Protease;Reference proteome;Serine protease;Signal;Zymogen |
| Interact With | |
| Induction | INDUCTION: Expression levels are not increased after blood feeding or cold shock, septic wounding, bacterial injection, laminarin injection or CM-Sephadex bead injection. {ECO:0000269|PubMed:9359580}. |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..22; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 28,655 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |