| IED ID | IndEnz0002008752 |
| Enzyme Type ID | protease008752 |
| Protein Name |
Putative subtilisin-like proteinase 2 EC 3.4.21.- |
| Gene Name | SPL2 ECU03_1180 |
| Organism | Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Fungi incertae sedis Microsporidia Apansporoblastina Unikaryonidae Encephalitozoon Encephalitozoon cuniculi (Microsporidian parasite) Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite) |
| Enzyme Sequence | MFFVGVAVLAALQSVWGNGGLETNEVAGMDRLGVESQKENPPGILLRKDDGMCEARKPMDMSPGEVQTETKTVVKEIVVEIEEPREGIQEVLPVVQYEGQAKVSAGNDLLKPSCGVSSGFTSSAERCYVLTKDAHDGDTSKMISLVESLSGRVKRQYTKNITGVSFCSSHSDVLRKVDDAGMHVEEDKIYTVSMLQNNIPNYMYLMRHYENTIFNNYFYDNWIFRVLQIKRVMTKFLGSYEYYHTGKGVNIFLLDTAISSMDGACNLSGRLEACNAHGNVMAELLVGKTNGFAKDSRLSVLDVVDCDGKVALSEMIHGLEGLRESGGPSILVFGVSGPYSASLNSAVDRISSRGTVVVSPAGNSHDQSCNYSPGSSKSVINVGSVDKHAGISRFSNHGDCIRMFAPGEDVLQDSSLTGTSLSAAIVASSIALFLETSPRAAFPQIWGYLNQNSFWNSRGSYSVLKIPRLGCKGRIRGSIFRLGGLYEDIVPLVFVVLITSALLYLLLIGIRRFRRRREQELHDEDVLFDPPVDRF |
| Enzyme Length | 535 |
| Uniprot Accession Number | Q8SS86 |
| Absorption | |
| Active Site | ACT_SITE 255; /note=Charge relay system; /evidence=ECO:0000255|PROSITE-ProRule:PRU01240; ACT_SITE 277; /note=Charge relay system; /evidence=ECO:0000255|PROSITE-ProRule:PRU01240; ACT_SITE 420; /note=Charge relay system; /evidence=ECO:0000255|PROSITE-ProRule:PRU01240 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.21.- |
| Enzyme Function | FUNCTION: May be involved in the degradation of proteins for nutrient acquisition or possess a regulatory function by proteolytic activation of proproteins. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (1); Disulfide bond (1); Domain (1); Signal peptide (1); Transmembrane (1) |
| Keywords | Disulfide bond;Hydrolase;Membrane;Protease;Reference proteome;Serine protease;Signal;Transmembrane;Transmembrane helix |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..17; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 58,673 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |