Detail Information for IndEnz0002008828
IED ID IndEnz0002008828
Enzyme Type ID protease008828
Protein Name Serpin I2
Serine protease inhibitor 14
Gene Name Serpini2 Spi14
Organism Mus musculus (Mouse)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Euarchontoglires Glires (Rodents and rabbits) Rodentia Myomorpha (mice and others) Muroidea Muridae Murinae Mus Mus Mus musculus (Mouse)
Enzyme Sequence MNKTILWSFLLFFSGSQTSRATDQKIADFAVDLYKAISLSHKNNIIFSPLGTTMLLGMVQLGAKGKAQQQILKTLRMRGTPAGEEFSVLKSLFSAISKKKQEFTFNLASALYLQEGFIVKETYLHSNKEFFQSATKLVDFLDAKTSAQAISTWVESKTDGKIKNMFSEEEFGPLTRLVLVNAIYFKGDWKQKFRKEDTEMTDFTKKDGSTVKVPMMKALLRAQYGYFSQSSMTCQVLELPYKADEFSLVIILPTEDTSIEEVENQVTAPHVRRWFSELHEEEVEVSLPRFKIEQKLDLKEALYSLNVTEIFSGGCDLSGITDSSEVYVSRVMQKVFFEINEDGSEAAASTGINIPAIMSLTQTQFLANHPFLFILKHIRTESILFMGKVTDPDIQTTKGRDLDSL
Enzyme Length 405
Uniprot Accession Number Q9JK88
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Glycosylation (1); Sequence conflict (5); Signal peptide (1); Site (1)
Keywords Glycoprotein;Protease inhibitor;Reference proteome;Secreted;Serine protease inhibitor;Signal
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..18; /evidence=ECO:0000255
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID 11217851; 12466851; 16184191; 21677750; 28071719;
Motif
Gene Encoded By
Mass 45,776
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda