Detail Information for IndEnz0002008850
IED ID IndEnz0002008850
Enzyme Type ID protease008850
Protein Name Subtilisin propeptide-like protein
PfSUB1-ProM
Gene Name PF3D7_0507400
Organism Plasmodium falciparum (isolate 3D7)
Taxonomic Lineage cellular organisms Eukaryota Sar Alveolata Apicomplexa Aconoidasida Haemosporida (haemosporidians) Plasmodiidae Plasmodium Plasmodium (Laverania) Plasmodium falciparum Plasmodium falciparum (isolate 3D7)
Enzyme Sequence MKFLFAFNFFSLYIYLYEFLCIHLCGSQVTPAGTVLNSNSALISRRINRRKMKNCNNNDLLKVLKMETTYNELPAHNLLMSSKNDINKLFDYINKNEELSKLMNSCGTYVYLKYLGVVIFSIKENVQISHLSEFIQYLLNKNVCIEFNQNVML
Enzyme Length 153
Uniprot Accession Number C0H4D0
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Acts as a specific inhibitor of subtilisin-like protease SUB1. {ECO:0000269|PubMed:31942933}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Region (1); Signal peptide (1)
Keywords Cell membrane;Membrane;Reference proteome;Secreted;Signal
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:31942933}. Parasitophorous vacuole lumen {ECO:0000305|PubMed:31942933}. Cell membrane {ECO:0000305|PubMed:31942933}; Peripheral membrane protein {ECO:0000305}; Extracellular side {ECO:0000305}.
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..27; /evidence=ECO:0000255
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 17,892
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda