| IED ID |
IndEnz0002008926 |
| Enzyme Type ID |
protease008926 |
| Protein Name |
Cystein proteinase inhibitor protein salarin
|
| Gene Name |
salarin |
| Organism |
Salvelinus alpinus (Arctic char) (Salmo alpinus) |
| Taxonomic Lineage |
cellular organisms
Eukaryota
Opisthokonta
Metazoa
Eumetazoa
Bilateria
Deuterostomia
Chordata
Craniata
Vertebrata
Gnathostomata (jawed vertebrates)
Teleostomi
Euteleostomi
Actinopterygii
Actinopteri
Neopterygii
Teleostei
Osteoglossocephalai
Clupeocephala
Euteleosteomorpha
Protacanthopterygii
Salmoniformes (salmons and trouts)
Salmonidae (salmonids)
Salmoninae (trouts
salmons & chars)
Salvelinus
Salvelinus alpinus (Arctic char) (Salmo alpinus)
|
| Enzyme Sequence |
MKSLVLLLLVAVTVSSVVSKPLPEDSEAEVHKEFETWKVKYGKSYPSTEEEAKRKEMWLATRKRVMEHNTRAGNGLESYTMAVNHFADLTTEEVPKGLLPMPRPEEEEVDKEFEMWKTVNGKTYNSTEEEARRKEIWLATRARVMEHNKRAENGSESFTMGINYFSDMTFEEVPKGRLMVVFPTRDGGEEAEVDKEFEMWKVQHGKSYGSTEEEAKRKEIWLATRTRVMEHNKRAETGLESFTMGMNHLSDKTTAEVTGQRLQDREEAEVHKEFETWKVKYGKTYPSTEEEAKRKEIWLATRKMVTEHNKRAENGQESFTMAVNHFADLTTEEVPKGLLPME |
| Enzyme Length |
342 |
| Uniprot Accession Number |
Q70SU7 |
| Absorption |
|
| Active Site |
|
| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
|
| Enzyme Function |
FUNCTION: Inhibits papain and ficin (cysteine proteinases) but not trypsin (a serine proteinase). {ECO:0000250|UniProtKB:Q70SU8}. |
| Temperature Dependency |
|
| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
|
| Features |
Chain (1); Glycosylation (2); Signal peptide (1) |
| Keywords |
Cytoplasm;Direct protein sequencing;Glycoprotein;Protease inhibitor;Signal;Thiol protease inhibitor;Vacuole |
| Interact With |
|
| Induction |
|
| Subcellular Location |
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q70SU8}. Vacuole {ECO:0000250|UniProtKB:Q70SU8}. |
| Modified Residue |
|
| Post Translational Modification |
PTM: N-glycosylated, with sialylated biantennary complex-type glycans. {ECO:0000250|UniProtKB:Q70SU8}.; PTM: O-glycosylated, with sialylated oligosaccharides. {ECO:0000250|UniProtKB:Q70SU8}. |
| Signal Peptide |
SIGNAL 1..19; /evidence=ECO:0000269|PubMed:14505823 |
| Structure 3D |
|
| Cross Reference PDB |
- |
| Mapped Pubmed ID |
- |
| Motif |
|
| Gene Encoded By |
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| Mass |
39,689 |
| Kinetics |
|
| Metal Binding |
|
| Rhea ID |
|
| Cross Reference Brenda |
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