Detail Information for IndEnz0002008949
IED ID IndEnz0002008949
Enzyme Type ID protease008949
Protein Name Serpin B10
Gene Name SERPINB10
Organism Papio anubis (Olive baboon)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Euarchontoglires Primates Haplorrhini Simiiformes Catarrhini Cercopithecoidea Cercopithecidae (Old World monkeys) Cercopithecinae Papio (baboons) Papio anubis (Olive baboon)
Enzyme Sequence MDTLATSINQFALELSKKLAESAQGKNIFFSSWSISTSLAMVYLGTKGTTAAQMGQVLQFNRDQGVKSSPESEKKRKMEFNSSNSEEIHSDFHTLISEILKPNDDYLLKTANAIYGEKTYPFHNKYLEDMKTYFGAEPQSVNFVEASDQIRKEINSWVERQTEGKIQNLLPDDSVDSTTRMILVNALYFKGIWEHQFLVQNTTEKPFRINETTSKPVQMMFMKKKLQIFHIEKPQAVGLQLYYKSRDLSLLILLPEDINGLVQLEKDITYEKLNEWTSADMMELYEVQLHLPKFKLEDSYDLKSTLSSMGMSDAFSQSKADFSGMSSARNLFLSNVFHKAFVEINEQGTEAAAGTGSEIESRIRVPSIEFNANHPFLFFIRHNKTNSILFYGRLCSP
Enzyme Length 397
Uniprot Accession Number A9RA96
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Protease inhibitor that may play a role in the regulation of protease activities during hematopoiesis and apoptosis induced by TNF. May regulate protease activities in the cytoplasm and in the nucleus (By similarity). {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Compositional bias (1); Motif (1); Region (1); Site (1)
Keywords Cytoplasm;Nucleus;Protease inhibitor;Reference proteome;Serine protease inhibitor
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif MOTIF 74..77; /note=Nuclear localization signal; /evidence=ECO:0000250
Gene Encoded By
Mass 45,383
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda