Detail Information for IndEnz0002009105
IED ID IndEnz0002009105
Enzyme Type ID protease009105
Protein Name Probable 26S proteasome non-ATPase regulatory subunit 3
26S proteasome subunit S3
26S proteasome regulatory subunit RPN3
Diphenol oxidase A2 component
DOX-A2
Gene Name DOXA2 DOX-A2
Organism Anopheles stephensi (Indo-Pakistan malaria mosquito)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Panarthropoda Arthropoda Mandibulata Pancrustacea Hexapoda Insecta Dicondylia Pterygota (winged insects) Neoptera Endopterygota Diptera Nematocera Culicomorpha Culicoidea Culicidae (mosquitos) Anophelinae Anopheles Cellia Neocellia Anopheles stephensi (Indo-Pakistan malaria mosquito)
Enzyme Sequence MVSQTATPTATAASEPIVDVEMESAEDAETAKKDAELLAVQEIRDHARQIDKAVVSKEPRFILRVLRSLPTTRRKLALVVVGSLAVQLYPAGPERDGNQWAYIEDYPAGAQEPEGLHDPGSDKSPFAQEVDAYFHLLLLVRLLDKNDLPKATKCSQDLMAKIVGQNRRSLDLIAAKCYFYHSRVSELNNDLESIRSFLHSRLRTATLRNDFEGQAVLINCLLRNYLHYSLYDQADKLVNKSVFPETASNNECARFLYYLGRIKAAKLEYSVAHKQLVQALRKAPQQAAVGFRQTVQKLVIVVELLLGDIPERKVFRQAALRRSLGPYFQLTQAVRMGNLQRFGEVLENFGEQFRQDHTFTLIIRLRHNVIKTAIRSIGLAYSRISPQDIARKLGLDSPEDAEFIVAKAIRDGVIDATLDPEKGYMRTKESTDIYSTREPQLAFHQRISFCLDLHNQSVKAMRYPPKSYGKELESAEERREREQQDLELAKEMAEEDDDDF
Enzyme Length 500
Uniprot Accession Number Q9U5Z8
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Compositional bias (1); Domain (1); Region (1)
Keywords Proteasome;Reference proteome
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 56,841
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda