IED ID |
IndEnz0002009173 |
Enzyme Type ID |
protease009173 |
Protein Name |
Secretion monitor
|
Gene Name |
secM SDY_0127 |
Organism |
Shigella dysenteriae serotype 1 (strain Sd197) |
Taxonomic Lineage |
cellular organisms
Bacteria
Proteobacteria
Gammaproteobacteria
Enterobacterales
Enterobacteriaceae
Shigella
Shigella dysenteriae
Shigella dysenteriae serotype 1 (strain Sd197)
|
Enzyme Sequence |
MSGILTRWRQFGKRYFWPHLLLGMVAASLGLPALSNAAEPNAPAKATTRNHEPSAKVNFGQLALLEANTRHPNSNYSVDYWHQHAIRTVIRHLSFAMAPQTLPVAEESLPLQAQHLALLDTLSALLTQEGTPSEKGYRIDYAHFTPQAKFSTPVWISQAQGIRAGPQRLS |
Enzyme Length |
170 |
Uniprot Accession Number |
Q32JZ5 |
Absorption |
|
Active Site |
|
Activity Regulation |
|
Binding Site |
|
Calcium Binding |
|
catalytic Activity |
|
DNA Binding |
|
EC Number |
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Enzyme Function |
FUNCTION: Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation. {ECO:0000255|HAMAP-Rule:MF_01332}. |
Temperature Dependency |
|
PH Dependency |
|
Pathway |
|
nucleotide Binding |
|
Features |
Chain (1); Erroneous initiation (1); Signal peptide (1) |
Keywords |
Cytoplasm;Periplasm;Reference proteome;Signal |
Interact With |
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Induction |
|
Subcellular Location |
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000255|HAMAP-Rule:MF_01332}. Periplasm {ECO:0000255|HAMAP-Rule:MF_01332}. Note=The active form is cytosolic, while the periplasmic form is rapidly degraded, mainly by the tail-specific protease. {ECO:0000255|HAMAP-Rule:MF_01332}. |
Modified Residue |
|
Post Translational Modification |
|
Signal Peptide |
SIGNAL 1..37; /evidence=ECO:0000255|HAMAP-Rule:MF_01332 |
Structure 3D |
|
Cross Reference PDB |
- |
Mapped Pubmed ID |
- |
Motif |
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Gene Encoded By |
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Mass |
18,846 |
Kinetics |
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Metal Binding |
|
Rhea ID |
|
Cross Reference Brenda |
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