| IED ID | IndEnz0002009208 |
| Enzyme Type ID | protease009208 |
| Protein Name |
Trypsin EC 3.4.21.4 |
| Gene Name | |
| Organism | Pleuronectes platessa (European plaice) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Actinopterygii Actinopteri Neopterygii Teleostei Osteoglossocephalai Clupeocephala Euteleosteomorpha Neoteleostei Eurypterygia Ctenosquamata Acanthomorphata Euacanthomorphacea Percomorphaceae Carangaria Pleuronectiformes (flatfishes) Pleuronectoidei Pleuronectidae (righteye flounders) Pleuronectes Pleuronectes platessa (European plaice) |
| Enzyme Sequence | MRLLALLLMVGAAVAVPREDGRIIGGHECAAHSRPFMASLNYGYHFCGGVLINNQWVLSVAHCWYNPYAMQVMLGEHDLRKFEGTEQLMKTDTIIWHPNYDYQTLDLTSCSSSSTILWKVTHAVAPIPLPTSCPVAGTPCSVSGWGNTARDGDEVYLPTLLQCMDVPIVDEEQCMKSYPDMISPRMVCAGFMDGSRDACNGDSGSPLVCRGEVYGLVSWGQGCAQPNYPGVYVKLCEFLGWIERTLEAYP |
| Enzyme Length | 250 |
| Uniprot Accession Number | P35034 |
| Absorption | |
| Active Site | ACT_SITE 62; /note=Charge relay system; /evidence=ECO:0000250; ACT_SITE 106; /note=Charge relay system; /evidence=ECO:0000250; ACT_SITE 203; /note=Charge relay system; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.; EC=3.4.21.4; |
| DNA Binding | |
| EC Number | 3.4.21.4 |
| Enzyme Function | |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (1); Disulfide bond (6); Domain (1); Propeptide (1); Signal peptide (1); Site (1) |
| Keywords | Disulfide bond;Hydrolase;Protease;Secreted;Serine protease;Signal;Zymogen |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted, extracellular space. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..15; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 27,528 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |