Detail Information for IndEnz0002009274
IED ID IndEnz0002009274
Enzyme Type ID protease009274
Protein Name Pregnancy-associated glycoprotein 1
PAG 1
PAG1
EC 3.4.23.-
Gene Name
Organism Sus scrofa (Pig)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Laurasiatheria Artiodactyla Suina Suidae (pigs) Sus Sus scrofa (Pig)
Enzyme Sequence MKWLVILGLVALSECLVIIPLTKVKSIRENLREKDLLLNFLKEHPYNMIQKFGLKGSLCSPKISCLRLWNYLDMVYVGNITIGTPPQLFSVIFDTASSDLWVPSNQCHSRACVTHRSFNPTLSSTFQSSNRTVKLAPHSGLVSGLLGYDTVQIGRFKSENQAFGLSQSEPVKELENAFFDGVLGLGYPSLAIQGTTPVFDNLRKQGQIPEPVFALYLSTNTKKGSVLMIGGVDNNFFTGNLKWVPLSARNYWQITLDRITWRGVVVGCTRGCQAILDSGSAFLLGPSRQISSIQKIIQARFIENEYQVRCCARTTLADFIFTINNVQYPVPARAYIRKGSTPRRCYSNFSGGTESLGKEETWILGEVFLRLYFTVFDRGQNRIGLRIAV
Enzyme Length 389
Uniprot Accession Number Q29078
Absorption
Active Site ACT_SITE 94; /evidence=ECO:0000255|PROSITE-ProRule:PRU10094; ACT_SITE 277; /evidence=ECO:0000255|PROSITE-ProRule:PRU10094
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.4.23.-
Enzyme Function FUNCTION: Appears to be proteolytically inactive.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (2); Chain (1); Disulfide bond (3); Domain (1); Glycosylation (3); Propeptide (1); Signal peptide (1)
Keywords Aspartyl protease;Disulfide bond;Glycoprotein;Hydrolase;Protease;Reference proteome;Secreted;Signal;Zymogen
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Secreted, extracellular space.
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..15; /evidence=ECO:0000255
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 43,533
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda