Detail Information for IndEnz0002009299
IED ID IndEnz0002009299
Enzyme Type ID protease009299
Protein Name Zinc metalloproteinase MspA
EC 3.4.24.-
Gene Name mspA
Organism Legionella longbeachae
Taxonomic Lineage cellular organisms Bacteria Proteobacteria Gammaproteobacteria Legionellales Legionellaceae Legionella Legionella longbeachae
Enzyme Sequence MHHNYYLSPLAVALALGMVSPAKAADPILLQNASFSEVKQKFALSTQGVAVAKDSLSFVSEHTDRNKVTHVRMQQKYVGFPVYGGYAIMHSMNTAKSLAATTQSTVEMNGVVYQGLQTELGQPDASFVQNADKALQQFKAKYANQNVGDEKVIPMVYIDKDNQAHWAYKVSIRVNHLDKAPERPTAIIDARTQQPFVQWNDIKTERVSVKGSGFGGNKKMGYYEFGKDFPYLDLTRDANNATCYMENESVKVIDMKHKYSSVKAAMSFACSTTDSDIYSTGYREDNGALSPSNDALYAGYVIKHMYTDWYGVNVLSNSNGSPMQLVMRVHYGDGYENAYWDGEQMTFGCGDRMMYPLVSLGVGAHEISHGFTEQHSGLEYYGQSGGMNESFSDMAAQAAEHYSVGKSSWQIGGEIMKESSGYDALRYMDKPSRDGESIDTADEYYSGLDVHYSSGVYNHLFYILATKPNWDTRKAFDVMVKANMDYWTPYSSFDEGGCGVLSAAKDLGFSLNDVKSSLQAVAINYSKCH
Enzyme Length 529
Uniprot Accession Number P55110
Absorption
Active Site ACT_SITE 366; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095; ACT_SITE 451; /note=Proton donor; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.4.24.-
Enzyme Function
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (2); Chain (1); Metal binding (3); Propeptide (1); Signal peptide (1)
Keywords Hydrolase;Metal-binding;Metalloprotease;Protease;Signal;Zinc;Zymogen
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..24; /evidence=ECO:0000255
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 58,713
Kinetics
Metal Binding METAL 365; /note=Zinc; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095; METAL 369; /note=Zinc; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095; METAL 389; /note=Zinc; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095
Rhea ID
Cross Reference Brenda