| IED ID | IndEnz0002009321 |
| Enzyme Type ID | protease009321 |
| Protein Name |
26S proteasome non-ATPase regulatory subunit 3 26S proteasome regulatory subunit rpn-3 |
| Gene Name | rpn-3 C30C11.2 |
| Organism | Caenorhabditis elegans |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Nematoda (roundworms) Chromadorea Rhabditida Rhabditina Rhabditomorpha Rhabditoidea Rhabditidae Peloderinae Caenorhabditis Caenorhabditis elegans |
| Enzyme Sequence | MAPKTGETVVEKMEVDEAKQDVPATEPAKDLNAIAVENIKEQLAALDKGEEHLITRVLQVLPKTRKQINDNVLYKLVSSHLSSDAQFAEGMLKYLHYTPAADTEVQPMDTSNVKTKSPKKGVKPVFASPESDCYLRLLVLLHLYAQKKNTEALALGENQLTSIYNFDRRTLDGLAAKTLYFLCVIYEREGRLFDHQGFLNSRLRTATLRNFSESQAVLICWLLRCYLINRQYQSAAHLVSKVAFPDNASNNDLARYMYYQGRIKALQLDYNSAAGYFLQAQRKAPQEGAIGFKQAVQKWVVVIGLLQGEIPDRSVFRQPIYRKCLAHYLDLSRGVRDGDVARFNHNLEQFKTQFEADDTLTLIVRLRQNVIKTAIKQISLAYSRIYIKDIAKKLYITNETETEYIVAKAIADGAIDAVITSDVRDGPRYMQSSETADIYRTSEPQAHFDTRIRYCLELHNQAVKALRYPPKKKIAVETIEQAREREQQELEFAKELADEDDDDF |
| Enzyme Length | 504 |
| Uniprot Accession Number | Q04908 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Domain (1) |
| Keywords | Proteasome;Reference proteome |
| Interact With | Q95Y72 |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 10778742; 11099034; 11559592; 12437114; 12445391; 12529635; 12679813; 14551910; 14704431; 15338614; 15489339; 15791247; 17392428; 17486083; 17850180; 18182484; 18463287; 18692475; 18775730; 18829898; 18842813; 21085631; 21177967; 21529718; 22267497; 22500807; 22560298; 22634595; 23800452; 24884423; 25487147; 25753661; 26009280; 29348603; 31283754; 6593563; |
| Motif | |
| Gene Encoded By | |
| Mass | 57,507 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |