| IED ID | IndEnz0002009434 |
| Enzyme Type ID | protease009434 |
| Protein Name |
Serine protease inhibitor A3N Serpin A3N |
| Gene Name | Serpina3n Spi2 |
| Organism | Mus musculus (Mouse) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Euarchontoglires Glires (Rodents and rabbits) Rodentia Myomorpha (mice and others) Muroidea Muridae Murinae Mus Mus Mus musculus (Mouse) |
| Enzyme Sequence | MAFIAALGLLMAGICPAVLCFPDGTLGMDAAVQEDHDNGTQLDSLTLASINTDFAFSLYKELVLKNPDKNIVFSPLSISAALAVMSLGAKGNTLEEILEGLKFNLTETSEADIHQGFGHLLQRLNQPKDQVQISTGSALFIEKRQQILTEFQEKAKTLYQAEAFTADFQQPRQAKKLINDYVRKQTQGMIKELVSDLDKRTLMVLVNYIYFKAKWKVPFDPLDTFKSEFYAGKRRPVIVPMMSMEDLTTPYFRDEELSCTVVELKYTGNASALFILPDQGRMQQVEASLQPETLRKWKNSLKPRMIDELHLPKFSISTDYSLEDVLSKLGIREVFSTQADLSAITGTKDLRVSQVVHKAVLDVAETGTEAAAATGVKFVPMSAKLYPLTVYFNRPFLIMIFDTETEIAPFIAKIANPK |
| Enzyme Length | 418 |
| Uniprot Accession Number | Q91WP6 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Beta strand (17); Chain (1); Glycosylation (3); Helix (12); Region (1); Sequence conflict (1); Signal peptide (1); Site (1); Turn (4) |
| Keywords | 3D-structure;Acute phase;Glycoprotein;Protease inhibitor;Reference proteome;Secreted;Serine protease inhibitor;Signal |
| Interact With | |
| Induction | INDUCTION: Expression is induced by bacterial lipopolysaccharide (LPS). {ECO:0000269|PubMed:1718822}. |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000250}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..20; /evidence=ECO:0000255 |
| Structure 3D | X-ray crystallography (1) |
| Cross Reference PDB | 1YXA; |
| Mapped Pubmed ID | 15163632; 15618518; 15795238; 17015688; 21076990; 21267068; 21677750; 23012479; 24006456; 25299783; 25915831; 26624618; 29720086; 30304388; 30353127; 32599075; 32900484; 33436521; 33609775; 33662018; 34351428; |
| Motif | |
| Gene Encoded By | |
| Mass | 46,718 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |