| IED ID | IndEnz0002009438 |
| Enzyme Type ID | protease009438 |
| Protein Name |
Protein SpAN EC 3.4.24.- |
| Gene Name | SPAN |
| Organism | Strongylocentrotus purpuratus (Purple sea urchin) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Echinodermata Eleutherozoa Echinozoa Echinoidea (sea urchins) Euechinoidea Echinacea Camarodonta Echinidea Strongylocentrotidae Strongylocentrotus Strongylocentrotus purpuratus (Purple sea urchin) |
| Enzyme Sequence | MKLVLLLAGFAALAKCSLAAPAGVQKDIPMETSAPEKPSEATTLGLLKTPKPEPKDEEPSPGAFQGDMMLTDDQLRKVEEAIDDQKAGRKKRKATIYESQRWSYKIIPYVIESSSSGQSSLIRSAMDHWEQNTCLRFEPLTSSHSSRLGHTSYISFFRGNGCWSHVGRSFTNQQQISIGPQCGYFGTIVHEIGHAIGFHHEQSRPDRDEYINVHFENVQSGREHNFAKYTWGSVTSSNVEYDVGSIMHYGGYGFSSNGRPTITTIDPRLNSRLGQRTALSAADIELANRIYECDDVEDCSNADECLNGGYHDADCDCVCPSSYSGDLCQDGGPTVRPADCSYRFTEMTGEITSPNYPSNYEDNTACVYEIEGPYGSTIELTFLDMEIETETLCRYDAVEVRKDDINSIGEKFCGNTLPPVQISSSNQMMVSFTSDPSITRRGFKATYVIIIQTTTVFSTTTLQTTPPSTTTLQTTNPSTTTLQTTNPSTTTLQTTDTPVIGSCGGTFVGVEGRVASPNYPNDYDNSLQCDYVIEVDDGRRVELIFEDFGLEDETTCRWDSLMINLGNGIKVGMKMCGREYPAASLVSIGNRMELKLKTDGSVNDRGFVASYRAIDL |
| Enzyme Length | 616 |
| Uniprot Accession Number | P98068 |
| Absorption | |
| Active Site | ACT_SITE 191; /evidence=ECO:0000255|PROSITE-ProRule:PRU01211 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.24.- |
| Enzyme Function | |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (1); Chain (1); Disulfide bond (8); Domain (4); Metal binding (3); Propeptide (1); Region (2); Signal peptide (1) |
| Keywords | Cleavage on pair of basic residues;Developmental protein;Disulfide bond;EGF-like domain;Hydrolase;Metal-binding;Metalloprotease;Protease;Reference proteome;Repeat;Signal;Zinc |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..16; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 67,902 |
| Kinetics | |
| Metal Binding | METAL 190; /note=Zinc; via tele nitrogen; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU01211; METAL 194; /note=Zinc; via tele nitrogen; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU01211; METAL 200; /note=Zinc; via tele nitrogen; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU01211 |
| Rhea ID | |
| Cross Reference Brenda |