| IED ID |
IndEnz0002009470 |
| Enzyme Type ID |
protease009470 |
| Protein Name |
Putative zinc metalloprotease Rip3
|
| Gene Name |
rip3 MT2700 |
| Organism |
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) |
| Taxonomic Lineage |
cellular organisms
Bacteria
Terrabacteria group
Actinobacteria
Actinomycetia (high G+C Gram-positive bacteria)
Corynebacteriales
Mycobacteriaceae
Mycobacterium
Mycobacterium tuberculosis complex
Mycobacterium tuberculosis
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
|
| Enzyme Sequence |
MRDAIPLGRIAGFVVNVHWSVLVILWLFTWSLATMLPGTVGGYPAVVYWLLGAGGAVMLLASLLAHELAHAVVARRAGVSVESVTLWLFGGVTALGGEAKTPKAAFRIAFAGPATSLALSATFGALAITLAGVRTPAIVISVAWWLATVNLLLGLFNLLPGAPLDGGRLVRAYLWRRHGDSVRAGIGAARAGRVVALVLIALGLAEFVAGGLVGGVWLAFIGWFIFAAAREEETRISTQQLFAGVRVADAMTAQPHTAPGWINVEDFIQRYVLGERHSAYPVADRDGSITGLVALRQLRDVAPSRRSTTSVGDIALPLHSVPTARPQEPLTALLERMAPLGPRSRALVTEGSAVVGIVTPSDVARLIDVYRLAQPEPTFTTSPQDADRFSDAG |
| Enzyme Length |
393 |
| Uniprot Accession Number |
P9WHR0 |
| Absorption |
|
| Active Site |
ACT_SITE 67; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095 |
| Activity Regulation |
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| Binding Site |
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| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
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| EC Number |
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| Enzyme Function |
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| Temperature Dependency |
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| PH Dependency |
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| Pathway |
|
| nucleotide Binding |
|
| Features |
Active site (1); Chain (1); Domain (2); Metal binding (2); Transmembrane (6) |
| Keywords |
CBS domain;Cell membrane;Hydrolase;Membrane;Metal-binding;Metalloprotease;Protease;Repeat;Transmembrane;Transmembrane helix;Zinc |
| Interact With |
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| Induction |
INDUCTION: A member of the dormancy regulon. Induced in response to reduced oxygen tension (hypoxia) and low levels of nitric oxide (NO). {ECO:0000269|PubMed:12953092}. |
| Subcellular Location |
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
| Modified Residue |
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| Post Translational Modification |
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| Signal Peptide |
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| Structure 3D |
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| Cross Reference PDB |
- |
| Mapped Pubmed ID |
- |
| Motif |
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| Gene Encoded By |
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| Mass |
41,480 |
| Kinetics |
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| Metal Binding |
METAL 66; /note=Zinc; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095; METAL 70; /note=Zinc; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095 |
| Rhea ID |
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| Cross Reference Brenda |
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