| IED ID | IndEnz0002009519 |
| Enzyme Type ID | protease009519 |
| Protein Name |
Trypsin-2 EC 3.4.21.4 Trypsin II Fragment |
| Gene Name | |
| Organism | Salmo salar (Atlantic salmon) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Actinopterygii Actinopteri Neopterygii Teleostei Osteoglossocephalai Clupeocephala Euteleosteomorpha Protacanthopterygii Salmoniformes (salmons and trouts) Salmonidae (salmonids) Salmoninae (trouts salmons & chars) Salmo Salmo salar (Atlantic salmon) |
| Enzyme Sequence | AAFATEDDKIVGGYECKAYSQPHQVSLNSGYHFCGGSLVNENWVVSAAHCYQSRVEVRLGEHNIQVTEGSEQFISSSRVIRHPNYSSYNIDNDIMLIKLSKPATLNTYVQPVALPTSCAPAGTMCTVSGWGNTMSSTADKNKLQCLNIPILSYSDCNNSYPGMITNAMFCAGYLEGGKDSCQGDSGGPVVCNGELQGVVSWGYGCAEPGNPGVYAKVCIFNDWLTSTMATY |
| Enzyme Length | 231 |
| Uniprot Accession Number | P35032 |
| Absorption | |
| Active Site | ACT_SITE 49; /note=Charge relay system; /evidence=ECO:0000250; ACT_SITE 93; /note=Charge relay system; /evidence=ECO:0000250; ACT_SITE 185; /note=Charge relay system; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.; EC=3.4.21.4; |
| DNA Binding | |
| EC Number | 3.4.21.4 |
| Enzyme Function | |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (1); Disulfide bond (6); Domain (1); Metal binding (4); Non-terminal residue (1); Propeptide (1); Signal peptide (1); Site (1) |
| Keywords | Calcium;Digestion;Disulfide bond;Hydrolase;Metal-binding;Protease;Reference proteome;Secreted;Serine protease;Signal;Zymogen |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted, extracellular space. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL <1..4; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 24,823 |
| Kinetics | |
| Metal Binding | METAL 61; /note=Calcium; /evidence=ECO:0000250; METAL 63; /note=Calcium; via carbonyl oxygen; /evidence=ECO:0000250; METAL 66; /note=Calcium; via carbonyl oxygen; /evidence=ECO:0000250; METAL 71; /note=Calcium; /evidence=ECO:0000250 |
| Rhea ID | |
| Cross Reference Brenda |