| IED ID |
IndEnz0002009555 |
| Enzyme Type ID |
protease009555 |
| Protein Name |
Serpin B8
|
| Gene Name |
SERPINB8 |
| Organism |
Bos taurus (Bovine) |
| Taxonomic Lineage |
cellular organisms
Eukaryota
Opisthokonta
Metazoa
Eumetazoa
Bilateria
Deuterostomia
Chordata
Craniata
Vertebrata
Gnathostomata (jawed vertebrates)
Teleostomi
Euteleostomi
Sarcopterygii
Dipnotetrapodomorpha
Tetrapoda
Amniota
Mammalia
Theria
Eutheria
Boreoeutheria
Laurasiatheria
Artiodactyla
Ruminantia
Pecora
Bovidae
Bovinae
Bos (oxen
cattle)
Bos taurus (Bovine)
|
| Enzyme Sequence |
MDALCEANGTFAINLLKMLGEEDHLRNVFFSPLSLSSVLTMVLMGAKGNTAAQMSQALCLNESGDVHRGFQSLLREVSTSGPKCLLRTANRLFGEKTCDFLPAFKESCQKFYQADLEELSFAEDTEECRKHINDWVMEKTDGKISEILGAGTVSPLTKLVLVNAIYFKGKWNEQFDRKHTRGMPFKTNQEKKTVQMMFKQAKFKMGHVEEVPAQVLELPYVGAELSMLILLPDENTDLAVVEKALTYEKFRTWTSPEKLTEEKVQVFLPRLKLEASYDLEAFLRSLGMTDAFEEAKADFSGMSAKKNVPMSKVAHKCFVEVNEEGTEAAGATAVVRNSRCCRMEPKFCADHPFLFFIRHRETNSILFCGRFSSP |
| Enzyme Length |
374 |
| Uniprot Accession Number |
Q5BIR5 |
| Absorption |
|
| Active Site |
|
| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
|
| Enzyme Function |
FUNCTION: Has an important role in epithelial desmosome-mediated cell-cell adhesion. {ECO:0000250|UniProtKB:P50452}. |
| Temperature Dependency |
|
| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
|
| Features |
Chain (1); Site (1) |
| Keywords |
Cytoplasm;Protease inhibitor;Reference proteome;Serine protease inhibitor |
| Interact With |
|
| Induction |
|
| Subcellular Location |
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. |
| Modified Residue |
|
| Post Translational Modification |
|
| Signal Peptide |
|
| Structure 3D |
|
| Cross Reference PDB |
- |
| Mapped Pubmed ID |
- |
| Motif |
|
| Gene Encoded By |
|
| Mass |
42,173 |
| Kinetics |
|
| Metal Binding |
|
| Rhea ID |
|
| Cross Reference Brenda |
|