| IED ID | IndEnz0002009562 |
| Enzyme Type ID | protease009562 |
| Protein Name |
Transglutaminase-activating metalloprotease inhibitor TAMEP inhibitor P14 |
| Gene Name | sti |
| Organism | Streptomyces mobaraensis (Streptoverticillium mobaraense) |
| Taxonomic Lineage | cellular organisms Bacteria Terrabacteria group Actinobacteria Actinomycetia (high G+C Gram-positive bacteria) Streptomycetales Streptomycetaceae Streptomyces Streptomyces mobaraensis (Streptoverticillium mobaraense) |
| Enzyme Sequence | MRYITGGIALGSALILGSLVGAGATASATPAPAPAAQQSLYAPSALVLTVGQGDKAASAGVQRAVTLNCMPKPSGTHPDARGACDQLRAASGNFAEITKIKSGTACTKEWNPFVVTAEGVWEGQRVKYEHTFANPCEMKAGKGTVFEF |
| Enzyme Length | 148 |
| Uniprot Accession Number | P83544 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: Inhibits transglutaminase-activating metalloprotease. {ECO:0000269|PubMed:12869197}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Beta strand (6); Chain (1); Disulfide bond (2); Helix (4); Sequence conflict (2); Signal peptide (1); Site (1); Turn (2) |
| Keywords | 3D-structure;Direct protein sequencing;Disulfide bond;Protease inhibitor;Secreted;Serine protease inhibitor;Signal |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:12869197}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..38; /evidence=ECO:0000269|PubMed:12869197 |
| Structure 3D | X-ray crystallography (1) |
| Cross Reference PDB | 6I0I; |
| Mapped Pubmed ID | 31420998; |
| Motif | |
| Gene Encoded By | |
| Mass | 15,170 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |