| IED ID |
IndEnz0002009602 |
| Enzyme Type ID |
protease009602 |
| Protein Name |
C2H2 finger domain transcription factor mtfA
|
| Gene Name |
mtfA AFUB_095620 |
| Organism |
Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) (Aspergillus fumigatus) |
| Taxonomic Lineage |
cellular organisms
Eukaryota
Opisthokonta
Fungi
Dikarya
Ascomycota
saccharomyceta
Pezizomycotina
leotiomyceta
Eurotiomycetes
Eurotiomycetidae
Eurotiales (green and blue molds)
Aspergillaceae
Aspergillus
Aspergillus subgen. Fumigati
Neosartorya fumigata (Aspergillus fumigatus)
Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) (Aspergillus fumigatus)
|
| Enzyme Sequence |
MDVASLISPSESDTVPTFRSRSIQNSSASHYKRLSEQSTGSYFSAVPTHTTSYSRTPQPPLSPPAEDQSKCSLPSISILLENADGAAAHAAKRQRNSLSTHRDSDPRPPYDSITPHAMPPTPPLRPGSGFHSNGHSPSTSSVSAASSSALMKNTESYPQAPIGLPSPTDRSSISSQGSVQHAASAPYASPAPSVSSFSSPIEPSTPSTAAYYQRNPAPNTFQNPSPFPQTSTASLPSPGHQQMISPVTPAWQHHHYFPPSSSTSYQQNHDRYICRTCHKAFSRPSSLRIHSHSHTGEKPFRCTHAGCGKAFSVRSNMKRHERGCHTGRPVATAMVQ |
| Enzyme Length |
336 |
| Uniprot Accession Number |
B0YDH7 |
| Absorption |
|
| Active Site |
|
| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
|
| Enzyme Function |
FUNCTION: Transcription factor that controls morphogenesis and virulence. Acts as a positive regulator of gliotixin and protease production. {ECO:0000269|PubMed:24728192}. |
| Temperature Dependency |
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| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
|
| Features |
Chain (1); Compositional bias (3); Region (1); Zinc finger (2) |
| Keywords |
Metal-binding;Nucleus;Repeat;Transcription;Transcription regulation;Virulence;Zinc;Zinc-finger |
| Interact With |
|
| Induction |
|
| Subcellular Location |
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:24728192}. |
| Modified Residue |
|
| Post Translational Modification |
|
| Signal Peptide |
|
| Structure 3D |
|
| Cross Reference PDB |
- |
| Mapped Pubmed ID |
- |
| Motif |
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| Gene Encoded By |
|
| Mass |
36,076 |
| Kinetics |
|
| Metal Binding |
|
| Rhea ID |
|
| Cross Reference Brenda |
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