Detail Information for IndEnz0002009681
IED ID IndEnz0002009681
Enzyme Type ID protease009681
Protein Name Proteasome subunit alpha type-4-A
20S proteasome alpha subunit C-1
Proteasome 27 kDa subunit
Proteasome component 9
Proteasome subunit alpha type-3
Gene Name PAC1 PRC9 PRS1 At3g22110 MKA23.2
Organism Arabidopsis thaliana (Mouse-ear cress)
Taxonomic Lineage cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae rosids malvids Brassicales Brassicaceae Camelineae Arabidopsis Arabidopsis thaliana (Mouse-ear cress)
Enzyme Sequence MSRRYDSRTTIFSPEGRLYQVEYAMEAIGNAGSAIGILSKDGVVLIGEKKVTSKLLQTSTSAEKMYKIDDHVACAVAGIMSDANILINTARVQAQRYTFMYQEPMPVEQLVQSLCDTKQGYTQFGGLRPFGVSFLFAGWDKHHGFQLYMSDPSGNYGGWKAAAVGANNQAAQSILKQDYKDDATREEAVELALKVLTKTMDSTSLTSEKLELAEVYLTPSKTVKYHVHSPESLTKLLVKHGVTQPAAETS
Enzyme Length 250
Uniprot Accession Number O81148
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Cross-link (2); Sequence conflict (1)
Keywords Cytoplasm;Isopeptide bond;Nucleus;Proteasome;Reference proteome;Ubl conjugation
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID 12952558; 15215502; 15769804; 15821981; 15923328; 16055689; 16336779; 16502469; 17825468; 18775970; 20405473; 20687615; 28627464;
Motif
Gene Encoded By
Mass 27,475
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda