| IED ID | IndEnz0002009700 |
| Enzyme Type ID | protease009700 |
| Protein Name |
Carboxypeptidase S1 homolog B EC 3.4.16.6 Serine carboxypeptidase B SPCB |
| Gene Name | SCPB ARB_06019 |
| Organism | Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton mentagrophytes) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Onygenales Arthrodermataceae (dermatophytes) Trichophyton Arthroderma benhamiae (Trichophyton mentagrophytes) Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton mentagrophytes) |
| Enzyme Sequence | MVSFCGVAACLLTVAGHLAQAQFPPKPEGVTVLESKFGSGARITYKEPGLCETTEGVKSYAGYVHLPPGTLRDFGVEQDYPINTFFWFFEARKDPENAPLGIWMNGGPGSSSMFGMMTENGPCFVNADSNSTRLNPHSWNNEDQPVQVGLSYDTLANFTRNLVTDEITKLEPGEPIPEQNATFLVGTYASRNMNTTAHGTRHAAMALWHFAQVWFQEFPGYHPRNNKISIATESYGGRYGPAFTAFFEEQNQKIKNGTWKGHEGTMHVLHLDTLMIVNGCIDRLVQWPAYPQMAYNNTYGIEAVNASIHAGMLDALYRDGGCRDKINHCRSLSSVSDPENLGINSTVNDVCKDAETFCSNDVRDPYTKLSGRNYYDIGQLDPSPFPAPFYMAWLNQPHVQAALGVPLNWTQSNDVVSTAFRAIGDYPRPGWLENLAFLLENGIKVSLVYGDRDYACNWFGGELSSLGINYTDTQEFHNAGYAGIQINSSYIGGQVRQYGNLSFARVYEAGHEVPSYQPETALQIFHRALFNKDIATGTKDTSSRMDRGKFYGTSGPADSFGFKNEPPPQHVHFCHILDTSTCTKEQIQSVENGTATIRSWIIVDSNSTSLFPEVVGSGEPTPTPMPGGATTLSAHGYLYDVTLWVVLLVSAIELVM |
| Enzyme Length | 656 |
| Uniprot Accession Number | D4AP52 |
| Absorption | |
| Active Site | ACT_SITE 234; /evidence=ECO:0000255|PROSITE-ProRule:PRU10074; ACT_SITE 453; /evidence=ECO:0000255|PROSITE-ProRule:PRU10074; ACT_SITE 511; /evidence=ECO:0000255|PROSITE-ProRule:PRU10074 |
| Activity Regulation | |
| Binding Site | BINDING 456; /note=Substrate; /evidence=ECO:0000250; BINDING 512; /note=Substrate; /evidence=ECO:0000250 |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=Preferential release of a C-terminal arginine or lysine residue.; EC=3.4.16.6; |
| DNA Binding | |
| EC Number | 3.4.16.6 |
| Enzyme Function | FUNCTION: Extracellular serine carboxypeptidase that contributes to pathogenicity. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Binding site (2); Chain (1); Disulfide bond (3); Glycosylation (14); Lipidation (1); Propeptide (1); Signal peptide (1) |
| Keywords | Carboxypeptidase;Cell membrane;Disulfide bond;GPI-anchor;Glycoprotein;Hydrolase;Lipoprotein;Membrane;Protease;Reference proteome;Signal;Virulence |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor, GPI-anchor {ECO:0000305}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..21; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 72,378 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |