Detail Information for IndEnz0002009736
IED ID IndEnz0002009736
Enzyme Type ID protease009736
Protein Name Serine protease SplA
EC 3.4.21.-
Gene Name splA MW1755
Organism Staphylococcus aureus (strain MW2)
Taxonomic Lineage cellular organisms Bacteria Terrabacteria group Firmicutes Bacilli Bacillales Staphylococcaceae Staphylococcus Staphylococcus aureus Staphylococcus aureus (strain MW2)
Enzyme Sequence MNENVMVKGLTALTILTSLGFAENISNQPHSIAKAEKNVKEITDATKEPYNSVVAFVGGTGVVVGKNTIVTNKHIAKSNDIFKNRVSAHHSSKGKGGGNYDVKDIVEYPGKEDLAIVHVHETSTEGLNFNKNVSYTKFADGAKVKDRISVIGYPKGAQTKYKMFESTGTINHISGTFMEFDAYAQPGNSGSPVLNSKHELIGILYAGSGKDESEKNFGVYFTPQLKEFIQNNIEK
Enzyme Length 235
Uniprot Accession Number Q8NVX5
Absorption
Active Site ACT_SITE 74; /note=Charge relay system; /evidence=ECO:0000250; ACT_SITE 113; /note=Charge relay system; /evidence=ECO:0000250; ACT_SITE 189; /note=Charge relay system; /evidence=ECO:0000250
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.4.21.-
Enzyme Function
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (3); Chain (1); Signal peptide (1)
Keywords Hydrolase;Protease;Secreted;Serine protease;Signal
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..35; /evidence=ECO:0000250
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 25,550
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda