| IED ID | IndEnz0002009999 |
| Enzyme Type ID | protease009999 |
| Protein Name |
Extracellular serine protease EC 3.4.21.- Fragment |
| Gene Name | prvA |
| Organism | Dichelobacter nodosus (Bacteroides nodosus) |
| Taxonomic Lineage | cellular organisms Bacteria Proteobacteria Gammaproteobacteria Cardiobacteriales Cardiobacteriaceae Dichelobacter Dichelobacter nodosus (Bacteroides nodosus) |
| Enzyme Sequence | MKLSHLSLAIISAITLAACGGGNDDKPMPQDPDNGALVEQRNEAIKKKATAYLEDKDGKAPALTKDEEATLSQIDENLFNEYKKKQKELENQASDDEVDPTKTGVVGNLDLGKQASQGTTQYVRGTKSSFDAENNPKEVSSATAILGVEAKTQNPWLTNIVLARKVRADGTVSIMQYLGNDGSDAADFTNVKSLQAQNDHNVVKFSDLKTNKPLDEAKLEAQKKQVDLIIKLYEKIDSSEITTEEKEELEKFVALKEELNAIDIKSPEGYVGLDEKAHKLFSETGASGSDDIIFGDDVPTNNSVLGTADTGSGAIPPVKPIYTSGKPGADATGAGALGLVGMNFKVGGTQEAIQGTEEKSQSSTRVFGRQYNTQSRAERKFNSYADAAVLALSSEKDLANAIAGITDQSELANITADMKNAKINYHLAVKPQKLDYVQYGRVTGNLDP |
| Enzyme Length | 448 |
| Uniprot Accession Number | P19577 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.21.- |
| Enzyme Function | FUNCTION: This enzyme is a chymotrypsin-like serine protease. Degrades a variety of substrates present in the skin and hoof of the sheep, including elastin, keratin, fibrinogen and collagen. It seems to play an important role in the pathogenesis of sheep footrot. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Non-terminal residue (1); Region (1); Signal peptide (1) |
| Keywords | Hydrolase;Protease;Serine protease;Signal |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..20; /evidence=ECO:0000255|PROSITE-ProRule:PRU00303 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 48,154 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |