| IED ID |
IndEnz0002010009 |
| Enzyme Type ID |
protease010009 |
| Protein Name |
Regulator of free ubiquitin chains 1
|
| Gene Name |
RFU1 KLLA0D05577g |
| Organism |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica) |
| Taxonomic Lineage |
cellular organisms
Eukaryota
Opisthokonta
Fungi
Dikarya
Ascomycota
saccharomyceta
Saccharomycotina (true yeasts)
Saccharomycetes
Saccharomycetales
Saccharomycetaceae
Kluyveromyces
Kluyveromyces lactis (Yeast) (Candida sphaerica)
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)
|
| Enzyme Sequence |
MKSSSHLKQEALNYRFNSNVPLKLYLTTCISIVEEAQNSARCNNMERAYLLYIRYLDLCLNRLVHHSEVNTSVESLYKREYFQLLKLEVPAIMKITEELKIKIDARYKSLANNVATSTYVRSPAVMTTNPSDEINLPSSFDEQKFNQSISWFNHSSKHFSAQSDSNNEYPELPELNATSTSVTYTMPAL |
| Enzyme Length |
189 |
| Uniprot Accession Number |
Q6CRY0 |
| Absorption |
|
| Active Site |
|
| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
|
| Enzyme Function |
FUNCTION: Inhibitor of the DOA4 deubiquitinase involved in the regulation of protein degradation by the proteasome and maintenance of a normal level of free ubiquitin. {ECO:0000250}. |
| Temperature Dependency |
|
| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
|
| Features |
Chain (1) |
| Keywords |
Endosome;Protease inhibitor;Reference proteome;Thiol protease inhibitor |
| Interact With |
|
| Induction |
|
| Subcellular Location |
SUBCELLULAR LOCATION: Endosome {ECO:0000250}. |
| Modified Residue |
|
| Post Translational Modification |
|
| Signal Peptide |
|
| Structure 3D |
|
| Cross Reference PDB |
- |
| Mapped Pubmed ID |
- |
| Motif |
|
| Gene Encoded By |
|
| Mass |
21,733 |
| Kinetics |
|
| Metal Binding |
|
| Rhea ID |
|
| Cross Reference Brenda |
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