| IED ID |
IndEnz0002010014 |
| Enzyme Type ID |
protease010014 |
| Protein Name |
26S proteasome regulatory subunit RPN11
|
| Gene Name |
RPN11 AGR006W |
| Organism |
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii) |
| Taxonomic Lineage |
cellular organisms
Eukaryota
Opisthokonta
Fungi
Dikarya
Ascomycota
saccharomyceta
Saccharomycotina (true yeasts)
Saccharomycetes
Saccharomycetales
Saccharomycetaceae
Eremothecium
Eremothecium gossypii (Yeast) (Ashbya gossypii)
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)
|
| Enzyme Sequence |
MDRLQRLMMSQRSNMIGAAATEMPLDDTKETVYISSLALLKMLKHSRAGVPMEVMGLMLGDFVDEYTVNVVDVFAMPQSGTGVSVEAVDDVFQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVDTQRSFEQLNSRAVAVVVDPIQSVKGKVVIDAFRLISPATVVRNQEPRQTTSNVGLLNKPNIQSLIHGLNRHYYSLNIDYHKTSAELNMLMNLHKEQWQSGLKMHDYKEKERINLEATKKSVRIAEQYTKRIEEEKELTEDELKTRYVGKQDPKKHLSETAERVLEENIVSVLTAGVNSVAIK |
| Enzyme Length |
311 |
| Uniprot Accession Number |
Q750E9 |
| Absorption |
|
| Active Site |
|
| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
|
| Enzyme Function |
FUNCTION: Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. {ECO:0000250}. |
| Temperature Dependency |
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| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
|
| Features |
Chain (1); Domain (1); Metal binding (3); Motif (1) |
| Keywords |
Hydrolase;Metal-binding;Metalloprotease;Protease;Proteasome;Reference proteome;Zinc |
| Interact With |
|
| Induction |
|
| Subcellular Location |
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| Modified Residue |
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| Post Translational Modification |
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| Signal Peptide |
|
| Structure 3D |
|
| Cross Reference PDB |
- |
| Mapped Pubmed ID |
- |
| Motif |
MOTIF 114..127; /note=JAMM motif; /evidence=ECO:0000255|PROSITE-ProRule:PRU01182 |
| Gene Encoded By |
|
| Mass |
35,202 |
| Kinetics |
|
| Metal Binding |
METAL 114; /note=Zinc; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU01182; METAL 116; /note=Zinc; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU01182; METAL 127; /note=Zinc; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU01182 |
| Rhea ID |
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| Cross Reference Brenda |
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