| IED ID | IndEnz0002010149 |
| Enzyme Type ID | protease010149 |
| Protein Name |
Venom serine protease EC 3.4.21.- allergen Pol d 4 |
| Gene Name | |
| Organism | Polistes dominula (European paper wasp) (Vespa dominula) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Panarthropoda Arthropoda Mandibulata Pancrustacea Hexapoda Insecta Dicondylia Pterygota (winged insects) Neoptera Endopterygota Hymenoptera Apocrita (wasps ants and bees) Aculeata Vespoidea Vespidae (wasps) Polistinae (paper wasps) Polistini Polistes Polistes dominula (European paper wasp) (Vespa dominula) |
| Enzyme Sequence | MNCGKIILLFITIIGVAKSREENCKCGWDNPSRIVNGVETEINEFPMVARLIYPSPGMYCGGTIITPQHIVTAAHCLQKYKRTNYTGIHVVVGEHDYTTDTETNVTKRYTIAEVTIHPNYNSHNNDIAIVKTNERFEYSMKVGPVCLPFNYMTRNLTNETVTALGWGKLRYNGQNSKVLRKVDLHVITREQCETHYGAAIANANLLCTFDVGRDACQNDSGGPILWRSPTTDNLILVGVVNFGRTCADDAPGGNARVTSFMEFIHNATIGETYCKAD |
| Enzyme Length | 277 |
| Uniprot Accession Number | Q7Z269 |
| Absorption | |
| Active Site | ACT_SITE 75; /note=Charge relay system; /evidence=ECO:0000250; ACT_SITE 126; /note=Charge relay system; /evidence=ECO:0000250; ACT_SITE 220; /note=Charge relay system; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.21.- |
| Enzyme Function | |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (1); Disulfide bond (3); Domain (1); Glycosylation (6); Signal peptide (1) |
| Keywords | Allergen;Disulfide bond;Glycoprotein;Hydrolase;Protease;Secreted;Serine protease;Signal |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000250}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..19; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 30,804 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |