| IED ID | IndEnz0002010357 |
| Enzyme Type ID | protease010357 |
| Protein Name |
Outer spore wall protein 4 Loss of heterozygosity protein 1 |
| Gene Name | LOH1 OSW4 YJL038C J1232 |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Saccharomycotina (true yeasts) Saccharomycetes Saccharomycetales Saccharomycetaceae Saccharomyces Saccharomyces cerevisiae (Baker's yeast) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
| Enzyme Sequence | MRFQLFIYFYFTIVVIAGTNTIQQFSDAGDRLITSLRNLDNNGTYETLTAEKVPIIEGQIQNISAKYEQHTFILKGLEAVLNYKVKSLDNNERESLEIEYEKVEKALDAALNVSPFEYIKKFKEVSRGKVVNALENLSREQNRITINGGREDEKEKEAREKKKRLDRIKRILTVSLLELGLAQGVADLCAVAPFACLLGVTVGSIGFIFWLALIYNAIQ |
| Enzyme Length | 219 |
| Uniprot Accession Number | P47055 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: Involved in spore wall assembly (PubMed:23966878). May be involved in maintaining genome integrity (PubMed:18562670). {ECO:0000269|PubMed:18562670, ECO:0000269|PubMed:23966878}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Glycosylation (3); Signal peptide (1); Topological domain (3); Transmembrane (2) |
| Keywords | Glycoprotein;Membrane;Reference proteome;Signal;Sporulation;Transmembrane;Transmembrane helix |
| Interact With | |
| Induction | INDUCTION: During sporulation. Repressed during vegetative growth by HST1 and RFM1. {ECO:0000269|PubMed:12612074, ECO:0000269|PubMed:9784122}. |
| Subcellular Location | SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}. |
| Modified Residue | |
| Post Translational Modification | PTM: N-glycosylated. {ECO:0000269|PubMed:19756047}. |
| Signal Peptide | SIGNAL 1..19; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 26928762; |
| Motif | |
| Gene Encoded By | |
| Mass | 24,843 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |