| IED ID |
IndEnz0002010423 |
| Enzyme Type ID |
protease010423 |
| Protein Name |
Putative zinc metalloprotease Rip3
|
| Gene Name |
rip3 ERDMAN_2885 |
| Organism |
Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman) |
| Taxonomic Lineage |
cellular organisms
Bacteria
Terrabacteria group
Actinobacteria
Actinomycetia (high G+C Gram-positive bacteria)
Corynebacteriales
Mycobacteriaceae
Mycobacterium
Mycobacterium tuberculosis complex
Mycobacterium tuberculosis
Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)
|
| Enzyme Sequence |
MRDAIPLGRIAGFVVNVHWSVLVILWLFTWSLATMLPGTVGGYPAVVYWLLGAGGAVMLLASLLAHELAHAVVARRAGVSVESVTLWLFGGVTALGGEAKTPKAAFRIAFAGPATSLALSATFGALAITLAGVRTPAIVISVAWWLATVNLLLGLFNLLPGAPLDGGRLVRAYLWRRHGDSVRAGIGAARAGRVVALVLIALGLAEFVAGGLVGGVWLAFIGWFIFAAAREEETRISTQQLFAGVRVADAMTAQPHTAPGWINVEDFIQRYVLGERHSAYPVADRDGSITGLVALRQLRDVAPSRRSTTSVGDIALPLHSVPTARPQEPLTALLERMAPLGPRSRALVTEGSAVVGIVTPSDVARLIDVYRLAQPEPTFTTSPQDADRFSDAG |
| Enzyme Length |
393 |
| Uniprot Accession Number |
H8EUF2 |
| Absorption |
|
| Active Site |
ACT_SITE 67; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095 |
| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
|
| Enzyme Function |
|
| Temperature Dependency |
|
| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
|
| Features |
Active site (1); Chain (1); Domain (2); Metal binding (2); Transmembrane (6) |
| Keywords |
CBS domain;Cell membrane;Hydrolase;Membrane;Metal-binding;Metalloprotease;Protease;Repeat;Transmembrane;Transmembrane helix;Zinc |
| Interact With |
|
| Induction |
INDUCTION: A member of the dormancy regulon. Induced in response to carbon monoxide (CO). It is hoped that this regulon will give insight into the latent, or dormant phase of infection. {ECO:0000269|PubMed:18474359}. |
| Subcellular Location |
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
| Modified Residue |
|
| Post Translational Modification |
|
| Signal Peptide |
|
| Structure 3D |
|
| Cross Reference PDB |
- |
| Mapped Pubmed ID |
- |
| Motif |
|
| Gene Encoded By |
|
| Mass |
41,480 |
| Kinetics |
|
| Metal Binding |
METAL 66; /note=Zinc; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095; METAL 70; /note=Zinc; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095 |
| Rhea ID |
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| Cross Reference Brenda |
|