| IED ID | IndEnz0002010518 |
| Enzyme Type ID | protease010518 |
| Protein Name |
Tricorn protease-interacting factor F2 EC 3.4.11.- |
| Gene Name | trf2 Ta0301 |
| Organism | Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165) |
| Taxonomic Lineage | cellular organisms Archaea Candidatus Thermoplasmatota Thermoplasmata Thermoplasmatales Thermoplasmataceae Thermoplasma Thermoplasma acidophilum Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165) |
| Enzyme Sequence | MNPGIEKYEIRFDFDLKDFTYTSHERIHLAGDWKDIKLDAVRLSVDKVTCNGQPMRFETGQDTVTVKGSFHDKDVIDIDFHAKVSDTLMGLYLSRTKEGTMITTQFESNGARMAFPCVDHPAYKAVFAITVVIDKDYDAISNMPPKRIEVSERKIVEFQDTPKMSTYLLYIGVGKFKYATDKYRDIDLILVSLKDIKSKYPLEIARKSIEFYESYFGIPYALPKMHLISVPEFGAGAMENWGAITFREVALMATENSGSIMKQNAAITIAHEIAHQWFGDLVTMKWWNDLWLNESFATFMSYKTVDSFSKQWDVFADFIRSETGGALRSDSLKNTHPIEVDVKDPDEISQIFDEISYGKGASILRMIEDYAGYEEFRKGISKYLNDHRYGNAEGSDLWTAIEDVSGKPVKRVMEYWIKNPGYPVVSVVKSGNKFRLTQEQFFLDGTRGQGKWPIPLTVMTKSGKKAMLMEESAEIEDMVKVNVNSSGFYRVSYDGESFETVMKNYSKLSNLDRWGLISDLYAFLISGRVSVDDYLARIKGFFEDSDHLIVEEIASQLTGLYLLKPDSNRIRETAASYLSRQVVALGDKQKGEDDKISKIRGIVTQDLAMVDDHFASDLARKFSTLAEDPDLALAKSIAAAKAYGISELASAADKYTDDEIRVRIIAAMGWCSPSDLKSVFELIDKGTIRKQDMLYVFSNMPANPKGRDFFFSNIDRIVALMEHAFEGTGYTSRILETAIPYLGLARYEDVKKKAEQIRKPSYNVGINKGLETLEIVRKLYNKL |
| Enzyme Length | 783 |
| Uniprot Accession Number | O93654 |
| Absorption | |
| Active Site | ACT_SITE 272; /note=Proton acceptor; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095 |
| Activity Regulation | |
| Binding Site | BINDING 107; /note=Substrate; /evidence=ECO:0000250 |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.11.- |
| Enzyme Function | FUNCTION: Proteases F1, F2 and F3 degrade oligopeptides produced by Tricorn (themselves probably produced by the proteasome), yielding free amino acids. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (1); Binding site (1); Chain (1); Metal binding (3); Region (1); Site (1) |
| Keywords | Aminopeptidase;Cytoplasm;Direct protein sequencing;Hydrolase;Metal-binding;Metalloprotease;Protease;Reference proteome;Zinc |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Cytoplasm. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 88,855 |
| Kinetics | |
| Metal Binding | METAL 271; /note=Zinc; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095; METAL 275; /note=Zinc; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095; METAL 294; /note=Zinc; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095 |
| Rhea ID | |
| Cross Reference Brenda |