| IED ID | IndEnz0002010976 |
| Enzyme Type ID | protease010976 |
| Protein Name |
Probable endopeptidase p60 EC 3.4.-.- Invasion-associated protein p60 |
| Gene Name | iap lin0591 |
| Organism | Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262) |
| Taxonomic Lineage | cellular organisms Bacteria Terrabacteria group Firmicutes Bacilli Bacillales Listeriaceae Listeria Listeria innocua Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262) |
| Enzyme Sequence | MNMKKATIAATAGIAVTAFAAPTIASASTVVVEAGDTLWGIAQSKGTTVDAIKKANNLTTDKIVPGQKLQVNEVATEEKAEKSVSATWLNVRSGAGVDHSILTSIKGGTKVTVETTESNGWHKITYNDGKTGYVNGKYLTDKATSTPVVKQEVKKETTQQVKPATEAKTEVKQPTTQQTAPAPKAAETKEAPVVDQNATTHNVKSGDTIWALSVKYGVSVQDIMSWNNLSSSSIYVGQKLAIKQPTKTVAPKAETKTQAPAAEKQTAPAVKENSNANTATTEKKETATEQQTTTKAPTQAAKPAPAPSTNTNKTNTTNNNTNASTPSKNTNTNTNTNTNTNTNQGSTNNASASALIAEAQKHLGKAYSWGGNGPTTFDCSGFTKYVFAKSGISLPRTSGAQYASTTRISESQAKPGDLVFFDYGSGISHVGIYVGNGQMINAQDNGVKYDNIHGAGWGKFLVGFGRV |
| Enzyme Length | 467 |
| Uniprot Accession Number | Q01836 |
| Absorption | |
| Active Site | ACT_SITE 379; /note=Nucleophile; /evidence=ECO:0000255|PROSITE-ProRule:PRU01284; ACT_SITE 429; /note=Proton acceptor; /evidence=ECO:0000255|PROSITE-ProRule:PRU01284; ACT_SITE 441; /evidence=ECO:0000255|PROSITE-ProRule:PRU01284 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.-.- |
| Enzyme Function | FUNCTION: This major extracellular protein may be involved in the invasion of non-professional phagocytic cells by Listeria. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (1); Compositional bias (2); Domain (4); Erroneous initiation (1); Natural variant (2); Region (3); Signal peptide (1) |
| Keywords | Hydrolase;Protease;Repeat;Signal;Thiol protease |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..27; /evidence=ECO:0000250 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 49,044 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |