| IED ID | IndEnz0002011095 |
| Enzyme Type ID | protease011095 |
| Protein Name |
Ubiquitin-like-specific protease 2 EC 3.4.22.- |
| Gene Name | ulp2 SPAC17A5.07c |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota Taphrinomycotina Schizosaccharomycetes Schizosaccharomycetales Schizosaccharomycetaceae Schizosaccharomyces Schizosaccharomyces pombe (Fission yeast) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
| Enzyme Sequence | MRDSKDALDDKSGSFTSLLPPFGKQRGTSPNDAIPIKSPLERLANSVTSPEKPTVRTAIQKDSPRRKQIDDDQTPPKHLKRSFQNVTVVSPRKKKTIDVVELPFTKGGYGGFYDPRPGCLKFTTHEINVSYTDTSIPVIHIPVQLLKRCCWLQGWRDNLVESPVHAIHLTLKNRDMKRITIGDSASLLFLYNPLHVESARAGLDLLDQSDFSLTSPSSAKEFKQLLTLKQSTIIPRTPQKTVRSIVKQTSSPHSSKMPKHSLPSSPTPFNSNSGDSLLSRIKNSNQSSSERPTANNGAQEQNQSSSSAGNTSNDFSTLCSQGSDKTLLSDASCTTILVYPFSGTNSIAITNTDLTRLNEGEFLNDTIVDFYLRYLYCKLQTQNPSLANDTHIFNTFFYNRLTSKDKDGKRLGHRGVRKWTQKVDLFHKKYIIVPINETFHWYLAIICNIDRLMPVDTKLEEQDEIVMSSVEQPSASKTRQAELTSNSPAILIFDSLANLHKGALNYLREYLLEEAFERKNVHLKSTDIRGFHAKVPQQSNFSDCGIYALHFVELFLETPEQVIANTLDKSLRRTDAKNFDQQWNLQKINTMRCDLKGLIRRLSTEWSSNNERQSLSSGSNDEEDKENDDDLAILPITN |
| Enzyme Length | 638 |
| Uniprot Accession Number | O13769 |
| Absorption | |
| Active Site | ACT_SITE 440; /evidence=ECO:0000250; ACT_SITE 494; /evidence=ECO:0000250; ACT_SITE 544; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.22.- |
| Enzyme Function | |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (1); Compositional bias (2); Modified residue (1); Region (3) |
| Keywords | Hydrolase;Nucleus;Phosphoprotein;Protease;Reference proteome;Thiol protease;Ubl conjugation pathway |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:16823372}. |
| Modified Residue | MOD_RES 526; /note=Phosphothreonine; /evidence=ECO:0000269|PubMed:18257517 |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 19547744; 20473289; 20625380; 21712547; 23173672; 23697806; 24362309; 24763107; 24818994; 25373780; 25720772; 26221037; 27298342; 27398807; 27984725; 29996109; 30726745; 34250083; |
| Motif | |
| Gene Encoded By | |
| Mass | 71,917 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |