| IED ID | IndEnz0002011180 |
| Enzyme Type ID | protease011180 |
| Protein Name |
Uterine plasmin/trypsin inhibitor UPTI |
| Gene Name | |
| Organism | Sus scrofa (Pig) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Laurasiatheria Artiodactyla Suina Suidae (pigs) Sus Sus scrofa (Pig) |
| Enzyme Sequence | MSRLCLSAALLLLLGALVASTPGDEESSLVRAGPPGFCREPPYTGPCSAHFVRYFYNATTGLCQSFVYGGCRGKQNNFMDEKECLHTCDTCAKAQGKRGNCASEMLKSTRPQGWAVAAFQMG |
| Enzyme Length | 122 |
| Uniprot Accession Number | Q29100 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: Inhibitor of plasmin and trypsin. Also has a weak affinity for chymotrypsin. Could serve to neutralize the activities of one or more serine proteinases generated by the proliferating trophoblast during the formation of the noninvasive placenta. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Disulfide bond (3); Domain (1); Propeptide (1); Sequence conflict (4); Signal peptide (1); Site (1) |
| Keywords | Direct protein sequencing;Disulfide bond;Protease inhibitor;Reference proteome;Serine protease inhibitor;Signal |
| Interact With | |
| Induction | INDUCTION: By progesterone. |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..20; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 13,109 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |